Con-current Oral Abstract Presentations Session 2

Spatial and Temporal Tuning of Synthetic Hydrogel Microenvironments for Promoting Neovascularization

biomimetic; hydrogel; tissue engineering

G. Papavasiliou, Illinois Institute of Technology, Chicago, IL

Spatiotemporal Dissolved Oxygen Concentrations from a Nanofiber Cell Seeded Scaffold

scaffolds; tissue engineering

D. T. Bowers, University of Virginia, Charlottesville, VA

E. Botchwey, Georgia Tech, Atlanta, Georgia

Visible light-mediated multi-scale thiol-ene hydrogels for 3D cell culture

biocompatibility/soft tissue; hydrogel; polymerization

H. Shih, Indiana University-Purdue University Indianapolis, Indianapolis, IN

A. K. Fraser, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana

C. Lin, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana

Photodegradable Microspheres as Templates for Model Alveoli Formation

degradation; epithelial cells; hydrogel

K. J. R. Lewis, University of Colorado at Boulder, Boulder, CO

M. W. Tibbitt, University of Colorado at Boulder, Boulder, Colorado

K. S. Anseth, University of Colorado at Boulder, Boulder, Colorado

A Biomimetic PEG Hydrogel to Evaluate the Effects of a Vasculogenic Co-culture on Hepatocyte Bioactivity

cell-cell interactions; hydrogel; tissue engineering

S. J. Higbee, Rice University, Houston, TX

J. L. West, Duke University, Houston, Texas

Aligned Conducting Polymer Nanotubes for On-Demand Release of Nerve Growth Factor and Contact Guidance of Neurons

controlled release; electrical stimulation; growth factor

M. R. Abidian, Pennsylvania State University, state College, PA

G. Yang, Pennsylvania State University, State College, Pennsylvania

Design and Characterization of Porous Poly(Propylene Fumarate) Sleeve Scaffolds

polymer; porosity; scaffolds

M. O. Wang, University of Maryland College Park, College Park, MD

C. E. Vorwald, University of Maryland, College Park, Maryland

M. L. Dreher, Food and Drug Administration, Silver Spring, MD, Maryland

E. J. Mott, Case Western Reserve University, Cleveland, Ohio

D. Dean, Case Western Reserve University, Cleveland, Ohio

J. P. Fisher, University of Maryland, College Park, Maryland

Polycaprolactone Fumarate (PCLF) as a Backbone for Chondrocyte Attachment and Proliferation Augmented by Platelet Lysate

bioresorbable; cartilage; cell differentiation

D. Bravo, Mayo Clinic, Rochester, MN

E. Wagner, Mayo Clinic, Rochester, Minnesota

D. Bravo, Mayo Clinic, Rochester, Minnesota

S. Chase, Mayo Clinic, Rochester, Minnesota

M. Dadsetan, Mayo Clinic, Rochester, Minnesota

S. Kakar, Mayo Clinic, Rochester, Minnesota

M. J. Yaszemski, Mayo Clinic, Rochester, Minnesota

Modular B-cell and T-cell Epitope Assembly in a Peptide-based Vaccine

immune response; in vivo; nanomedicine

R. R. Pompano, University of Chicago, Chicago, IL

J. Chen, University of Chicago, Chicago, Illinois

E. A. Verbus, University of Chicago, Chicago, Illinois

A. S. Chong, University of Chicago, Chicago, Illinois

J. H. Collier, University of Chicago, Chicago, Illinois

Tunable T cell immunity towards a protein antigen using polymersomes versus solid-core nanoparticles

immune response; nanomedicine

E. Scott, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland

A. Stano, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

K. Dane, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

M. A. Swartz, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

J. A. Hubbell, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

Finite Element Modeling of Strategies to Reduce the Foreign Body Response to Neural Electrodes Chronically Implanted in Brain Tissue

computer modeling/simulation; foreign body reactions (response); implant design

N. F. Nolta, University of Utah, Salt Lake City, UT

J. L. Skousen, University of Utah, Salt Lake City, Utah

M. B. Christensen, University of Utah, Salt Lake City, Utah

P. A. Tresco, University of Utah, Salt Lake City, Utah

Long Term Survival of PEGylated Murine Allogenic Islets using Short Course Immunomodulation

diabetes; encapsulated cells; immune response

J. A. Giraldo, University of Miami, Miami, FL

R. D. Molano, University of Miami, Miami, Florida

H. R. Rengifo, University of Miami, Miami, Florida

C. Fortino, University of Miami, Miami, Florida

C. Ricordi, University of Miami, Miami, Florida

A. Pileggi, University of Miami, Miami, Florida

C. L. Stabler, University of Miami, Miami, Florida

A dendritic cell-targeting microparticle vaccine for treatment of Type 1 Diabetes

diabetes; drug delivery/release; microspheres

J. S. Lewis, University of Florida, Gainesville, FL

M. Carstens, University of Florida, Gainesville, Florida

N. Dolgova, University of Florida, Gainesville, Florida

C. Xia, University of Florida, Gainesville, Florida

M. J. Clare-Salzler, University of Florida, Gainesville, Florida

B. G. Keselowsky, University of Florida, Gainesville, Florida

An Inflammation-responsive Hydrogel for Drug Delivery for Treatment of Ulcerative Colitis

animal model; drug delivery/release; sustained release

S. Zhang, Massachusetts Institute of Technology, Cambridge, MA

S. Zhang, Massachusetts Institute of Technology, cambridge, Massachusetts

J. Ermann, Brigham and Women's Hospital, Boston, Massachusetts

P. Vemula, Brigham and Women's Hospital, Cambridge, Massachusetts

R. Langer, Massachusetts Institute of Technology, Cambridge, Massachusetts

J. M. Karp, Brigham and Women's Hospital, Cambridge, Massachusetts

Non-spherical Artificial Antigen Presenting Cells for Tumor Immunotherapy

biomimetic; immune response; microspheres

J. C. Sunshine, Johns Hopkins School of Medicine, Baltimore, MD

K. Perica, Johns Hopkins School of Medicine, Baltimore, Maryland

J. P. Schneck, Johns Hopkins School of Medicine, Baltimore, Maryland

J. J. Green, Johns Hopkins School of Medicine, Baltimore, Maryland

Neutrophil extracellular traps on biomaterials?

blood-material interaction; cell-material interactions; immune response

C. Sperling, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

M. Fischer, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

C. Werner, Leibniz-Institute of Polymer Research Dresden, Dresden, Germany

Effects of Hydroxyapatite-Coating vs. Hydrophilic Surface on Early Healing of Dental Implant in an Ovine Model

ceramic; dental/endosteal implant; histomorphometry

J. Lee, Zimmer Dental Inc., Carlsbad, CA

H. Wen, Zimmer Dental Inc., Carlsbad, California

J. Bassett, Zimmer Dental Inc., Carlsbad, California

SiO2 and ZnO Dopants in 3D Printed TCP Scaffolds Enhances Osteogenesis and Angiogenesis in vivo

biodegradation; bone graft; calcium phosphate(s)

S. Bose, Washington State University, Pullman, WA

G. Fielding, Washington state university, Pullman, Washington

Fully Dense Nanocrystalline Hydroxyapatite as a Structural Material for Spinal Interbody Fusion

biomechanics; calcium phosphate(s); spinal implant

A. K. MacMillan, Pioneer Surgical Technology, Woburn, MA

L. Ferrara, Orthokinetic Technologies, Southport, North Carolina

T. J. Webster, Northeastern University, Boston, Massachusetts

J. Timothy, Spire Leeds Hosptial, Leeds, United Kingdom (Great Britain)

E. Ahn, N/A, Dover, Massachusetts

Injectable Polymer/β-TCP Biocomposite Delivery Systems for rhBMP-2

bone graft; calcium phosphate(s); tissue engineering

A. D. Talley, Vanderbilt University, Nashville, TN

E. M. Prieto, Vanderbilt University, Nashville, Tennessee

K. J. Zienkiewicz, Vanderbilt University, Nashville, Tennessee

T. Guda, University of Texas at San Antonio, Fort Sam Houston, Texas

P. Brown Baer, USAISR, Fort Sam Houston, Texas

D. T. Silliman, USAISR, Fort Sam Houston, Texas

S. A. Guelcher, Vanderbilt University, Nashville, Tennessee

Size Matters: Effects of PLGA-Microsphere Size in Injectable CPC/PLGA on Bone Formation

animal model; bone ingrowth; calcium phosphate(s)

J. van den Beucken, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands

Evaluation of a Gentamicin-Loaded Hydroxyapatite/Chitin Bone Cement

bone graft; drug delivery/release; hydroxy apatite

H. A. Doty, University of Memphis, Memphis, TN

R. Hay, Singapore General Hospital, Singapore, Singapore

T. H. Ong, National Cancer Center, Singapore, Singapore

H. M. Kam, National Cancer Center, Singapore, Singapore

A. K. S. Yew, Singapore General Hospital, Singapore, Singapore

C. M. Guo, Singapore General Hospital, Singapore, Singapore

Strontium Doped Calcium Phosphate Coatings on Biodegradable Magnesium Alloys

calcium phosphate(s); cell differentiation; surface modification

S. S. Singh, University of Pittsburgh, Pittsburgh, PA

A. Roy, University of Pittsburgh, Pittsburgh, Pennsylvania

B. Lee, University of Pittsburgh, Pittsburgh, Pennsylvania

P. N. Kumta, University of Pittsburgh, Pittsburgh, Pennsylvania

Effect of Local Alendronate Delivery on In Vivo Osteogenesis From PCL Coated 3D Printed TCP Scaffolds

biocompatibility/hard tissue; bone graft; calcium phosphate(s)

S. Bose, Washington State University, Pullman, WA

S. Tarafder, Washington State University, Pullman, Washington

Sodium Citrate Stabilized Calcium Phosphate Nanoparticles for the Sustained Delivery of Cisplatin

calcium phosphate(s); drug delivery/release; nanotechnology

E. E. Jacobs, University of Connecticut Health Center, Farmington, CT

J. L. Woodman, University of Connecticut Health Center, Farmington, Connecticut

L. T. Kuhn, University of Connecticut Health Center, Farmington, Connecticut

A Novel In-Situ Forming Calcium Polyphosphate System for Anti-Cancer Drug Release

calcium phosphate(s); drug delivery/release; embolization

A. Momeni, School of Biomedical Engineering, Dalhousie University, Halifax, NS, Canada

DEVELOPMENT OF A NOVEL TARGETED MICROPARTICLE DRUG DELIVERY SYSTEM FOR CANCER MEDICATION

drug delivery/release

C. E. Clark, Villanova University, Bryn Mawr, PA

Mimicking Platelet-Cancer Cell Interactions for Targeted Drug Delivery in Metastatic Breast Cancer

drug delivery/release; nanomedicine; platelet

C. Modery-Pawlowski, Case Western Reserve University, Cleveland, OH

A. Master, Case Western Reserve University, Cleveland, Ohio

V. Pan, Case Western Reserve University, Cleveland, Ohio

G. P. Howard, Case Western Reserve University, Cleveland, Ohio

A. Sen Gupta, Case Western Reserve University, Cleveland, Ohio

Biomaterial-mediated cancer-specific DNA delivery to liver cell cultures using synthetic poly(beta-amino esters)

gene therapy/gene delivery; nanomedicine; polymer

S. Y. Tzeng, Johns Hopkins University School of Medicine, Baltimore, MD

L. J. Higgins, Johns Hopkins University School of Medicine, Baltimore, Maryland

M. G. Pomper, Johns Hopkins University School of Medicine, Baltimore, Maryland

J. J. Green, Johns Hopkins University School of Medicine, Baltimore, Maryland

Molecular Farming and Engineering of a Filamentous Platform Technology to Deliver Therapies to Breast Cancer

drug delivery/release; nanomedicine

K. L. Lee, Case Western Reserve University, Cleveland Heights, OH

S. Shukla, Case Western Reserve University, Cleveland, Ohio

K. L. Lozada, Case Western Reserve University, Cleveland, Ohio

R. A. Keri, Case Western Reserve University, Cleveland, Ohio

N. F. Steinmetz, Case Western Reserve University, Cleveland, Ohio

Design of a Drug Eluting Stent for treatment of pancreatic malignancy

coating(s); drug delivery/release; tumor

L. Indolfi, Massachusetts Institute of Technology, Cambridge, MA

M. Ligorio, Massachusetts General Hospital, Boston, Massachusetts

D. Ting, Massachusetts General Hospital, Charlestown, Massachusetts

C. Ferrone, Massachusetts General Hospital, Boston, Massachusetts

J. W. Clark, Massachusetts General Hospital, Boston, Massachusetts

R. Langer, Massachusetts Institute of Technology, Cambridge, Massachusetts

E. R. Edelman, Massachusetts Institute of Technology, Cambridge, Massachusetts

Intrinsically radiopaque porous microspheres for improved transarterial chemoembolization

drug delivery/release; embolization; porosity

K. Saralidze, Maastricht University, Maastricht, Netherlands

Biocompatibility and degradation behavior of Mg-Sr alloy as temporary cardiovascular implants

biodegradation; cardiovascular; metal (alloys)

M. Bornapour, McGill University, Montreal, QC, Canada

M. Cerruti, McGill University, Montreal, Québec, Canada

D. Shum-Tim, McGill University, Montreal, Québec, Canada

M. Pekguleryuz, McGill University, Montreal, Québec, Canada

Evaluation of Failure Mechanisms of Utah Electrode Arrays in Rat Cortex

biocompatibility/soft tissue; immunohistochemistry; inflammation

M. B. Christensen, University of Utah, Salt Lake City, UT

N. F. Nolta, University of Utah, Salt Lake City, Utah

J. L. Skousen, University of Utah, Salt Lake City, Utah

P. A. Tresco, University of Utah, Salt Lake City, Utah

Histological and Clinical Evaluation of Failed Shoulder Surface Replacement Implants

histology; implant interface; in vivo

S. Ajami, UCL, Stanmore , Middlesex, United Kingdom (Great Britain)

M. Coathup, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

R. Olley, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

C. Wek, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

B. Bonnaud, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

S. Alexander, Royal National Orthopaedic Hospital, Stanmore, Middlesex, United Kingdom (Great Britain)

S. Lambert, Royal National Orthopaedic Hospital, Stanmore, Middlesex, United Kingdom (Great Britain)

C. Kelly, The Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom (Great Britain)

G. Blunn, UCL, Stanmore, Middlesex, United Kingdom (Great Britain)

Metal Bearing Surfaces in Total Joint Arthroplasty:  Do different joints display similar damage modes?

bearing surfaces; implant retrieval

F. Ansari, University of California, Berkeley, Berkeley, CA

E. Alvarez, Clemson University, Greenville, South Carolina

M. Harman, Clemson University, Clemson, South Carolina

L. Pruitt, University of California, Berkeley, Berkeley, California

M. Mayor, Dartmouth College, Hanover, New Hampshire

D. W. Van Citters, Dartmouth College, Hanover, New Hampshire

Investigating Keratin as a Biomimetic Coating for Percutaneous Device Applications

biomimetic

S. Jeyapalina, University of Utah, Salt Lake City, UT

M. Van Dyke, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

A. Sampson, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

D. H. Betz, University of Utah, Salt Lake City, Utah

R. D. Bloebaum, University of Utah, Salt Lake City, Utah

In vivo evaluation of device-associated inflammation using Positron Emission Tomography Imaging

foreign body reactions (response); in vivo; inflammation

J. ZHOU, University of Texas at Arlington, Arlington, TX

G. Hao, University of Texas Southwestern Medical Center, Dallas, Texas

H. Weng, University of Texas at Arlington, Arlington, Texas

Y. Tsai, University of Texas at Arlington, Arlington, Texas

D. W. Baker, University of Texas at Arlington, Arlington, Texas

X. Sun, University of Texas Southwestern Medical Center, Dallas, Texas

L. Tang, University of Texas at Arlington, Arlington, Texas

Atomic Force Microscopy Study of Coagulation Factor XII Interaction with Factor XI Autoactivation on Hydrophilic and Hydrophobic Surfaces

atomic force microscopy; blood-material interaction; coagulation factors

L. Xu, Penn State College of Medicine, Hershey, PA

C. Siedlecki, Penn State College of Medicine, Hershey, Pennsylvania

Adhesion of Vitronectin to Microfabricated Polymer Arrays

cell adhesion; protein adsorption

M. Rusin, Clemson University, Clemson, SC

Y. Mei, Clemson University, Charleston, South Carolina

D. Dean, Clemson University, Clemson, South Carolina

Elastomer Crosslink Density Affects Protein Adsorption and Conformation

adsorption; cell-material interactions; protein conformation

M. C. Vyner, Queen's University, Kingston, ON, Canada

L. Liu, McMaster University, Hamilton, Ontario, Canada

H. D. Sheardown, McMaster University, Hamilton, Ontario, Canada

B. G. Amsden, Queen's University, Kingston, Ontario, Canada

Preparation and Characterization of Collagen Substrates for Protein Interactions Studies

collagen; protein adsorption; surface characterization

D. G. Castner, University of Washington, Seattle, WA

E. H. Tronic, University of Washington, Seattle, Washington

R. Foster, University of Washington, Seattle, Washington

P. Koelsch, University of Washington, Seattle, Washington

Poly(trimethylene carbonate) Molecular Weight Affects Enzymatic Adsorption and Conformation, and Macrophage Behavior

degradation; enzyme(s); molecular weight

M. C. Vyner, Queen's University, Kingston, ON, Canada

A. Li, Queen's University, Kingston, Ontario, Canada

B. G. Amsden, Queen's University, Kingston, Ontario, Canada

Initial Cell Adhesion on RGD-immobilized Phospholipid Polymer Brush Layer with Different Molecular Mobility

cell-material interactions; polymer

Y. Inoue, The University of Tokyo, Tokyo, Japan

Y. Onodera, The University of Tokyo, Toyko, Japan

K. Ishihara, The University of Tokyo, Tokyo, Japan

Endothelial Cell Selective Surface for Modifying ePTFE Grafts

biomimetic; endothelialization; vascular graft

L. Dudash, Case Western Reserve University, Cleveland, OH

F. Kligman, Cleveland Clinic, Cleveland, Ohio

K. Kapalka, Case Western Reserve University, Cleveland, Ohio

K. Kottke-Marchant, Cleveland Clinic, Cleveland, Ohio

R. Marchant, Case Western Reserve University, Cleveland, Ohio

Interactions of Escherichia coli HM22 Biofilm with Electrochemically Active Commercially Pure Titanium Surface

cell-material interactions; orthopedic

J. Guo, Syracuse University, Syracuse, NY

J. L. Gilbert, Syracuse University, Syracus, New York