Con-current Oral Abstract Presentations Session 9

Cardiovascular Biomaterials and Blood Compatibility II

356

Partial Thromboplastin Time and Prothrombin Time for the Hemocompatibility Evaluation of Biomaterials

Q. Lu, U.S. Food and Drug Administration, Silver Spring, MD

M. A. Shamsie, U.S. Food and Drug Administration, Silver Spring, MD

J. M. Nehrer, U.S. Food and Drug Administration, Silver Spring, MD

R. A. Malinauskas, U.S. Food and Drug Administration, Silver Spring, MD

357

Development of a Model Surface for Bioprosthetic Heart Valves

M. M. Fahrenholtz, Rice University, Houston, TX

N. Dixit, University of California, Berkeley, Berkeley, CA

K. J. Grande-Allen, Rice University, Houston, TX

358

Hemocompatibility evaluation of elastomeric hollow fiber membranes as vascular grafts

A. E. Mercado-Pagan, Stanford University, Stanford, CA

D. Ker, Stanford University, Stanford, CA

Y. Yang, Stanford University, Stanford, CA

359

Modifying Venous Valve Biomaterial for Protein C Activation

J. J. Glynn, Oregon Health & Science University, Portland, OR

E. G. Polsin, University of Portland, Portland, OR

M. T. Hinds, Oregon Health & Science University, Portland, OR

360

Elastic/adhesive double-layered PLA-PEG multiblock copolymer membranes for prevention of cecum and cardiac adhesions

T. Yamaoka, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

E. Njatawidjaja, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

C. Agudelo, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

S. Kakinoki, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

A. Mahara, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan

361

Bio-Inspired, Engineered Microtopographies Reduce Platelet Adhesion and Activation on Blood-Contacting Materials

C. M. Kirschner, Sharklet Technologies, Inc., Aurora, CO

R. M. May, Sharklet Technologies, Inc., Aurora, CO

E. E. Mann, Sharklet Technologies, Inc., Aurora, CO

J. Fraser, Sharklet Technologies, Inc., Aurora, CO

C. A. Siedlecki, The Pennsylvania State University, Hershey, PA

A. B. Brennan, University of Florida, Gainesville, FL

S. T. Reddy, Sharklet Technologies, Inc., Aurora, CO

362

In Vitro and In Vivo Investigation of Nanostructured Vascular Patches

S. Grant, University of Missouri, Columbia, MO

A. Ostdiek, University of Missouri, Columbia, MO

D. Grant, University of Missouri, Columbia, MO

R. Gopaldas, University of Missouri, Columbia, MO

363

The Effects of Activated Non-Aggregated Platelets on Blood Plasma Coagulation

L. Xu, The Pennsylvania State University, College of Medicine, Hershey, PA

D. Grosz, Washington and Jefferson College, Washington, PA

E. A. Vogler, The Pennsylvania State University, University Park, PA

C. A. Siedlecki, The Pennsylvania State University College of Medicine, Hershey, PA

Cellular and Molecular Responses of Biomaterials at the Biomaterial-Tissue Interface I

365

Cell-Biomaterial Interface Cues Reinstate Declining Stemness in Aging Adult Stem Cells

S. W. Crowder, Vanderbilt University, Nashville, TN

D. A. Balikov, Vanderbilt University, Nashville, TN

H. N. Lewis, Vanderbilt University, Nashville, TN

C. M. Ambrose, Vanderbilt University, Nashville, TN

S. Lee, Vanderbilt University, Nashville, TN

H. Sung, Vanderbilt University, Nashville, TN

366

Photo-crosslinked Polymer Nanowires for Regulating Smooth Muscle Cells

X. Liu, University of Tennessee, Knoxville, TN

S. Wang, University of Tennessee, Knoxville, TN

367

Development of a Novel Optical Probe for In Vivo Detection of Biomaterial-Associated Apoptosis

l. tang, university of texas at arlington, Arlington, TX

J. ZHOU, UNIVERSITY OF TEXAS AT ARLINGTON, Arlington, TX

H. WENG, UNIVERSITY OF TEXAS AT ARLINGTON, Arlington, TX

Y. Tsai, University of Texas at Arlington, Arlington, TX

368

­­­In vivo assessment of guided neural stem cell differentiation in growth factor immobilized hydrogel scaffolds

H. Li, The University of Akron, Akron, OH

P. Sloan, Akron General Medical Center, Akron, OH

K. Bondor, Akron General Medical Center, Akron, OH

A. Koenig, The University of Akron, Akron, OH

N. Leipzig, The University of Akron, Akron, OH

369

Interaction of Electrically Stimulated Fibroblasts with Keratinocytes promotes Better Skin Equivalent Production

H. Park, Université Laval,

D. Rouabhia, Université Laval,

Z. Zhang, Saint-François d’Assise Hospital Research Center,

D. Lavertu, Saint-François d’Assise Hospital Research Center,

M. Rouabhia, Université Laval,

370

Wnt-BMP Cross-Talk Regulates Osteoblastic Differentiation of Human MSCs on Microstructured Surfaces

R. Olivares-Navarrete, Virginia Commonwealth University, Richmond, VA

S. L. Hyzy, Virginia Commonwealth University, Richmond, VA

C. A. Cundiff, Georgia Institute of Technology, Atlanta, GA

D. Haithcock, Georgia Institute of Technology, Atlanta, GA

C. Wasilewski, Georgia Institute of Technology, Atlanta, GA

Z. Schwartz, Virginia Commonwealth University, Richmond, VA

B. D. Boyan, Virginia Commonwealth University, Richmond, VA

Ceramics and Composites in Bone Tissue Engineering and Drug Delivery II

371

Functionalization of scaffolds with chimeric anti-BMP-2 monoclonal antibodies for osseous regeneration

S. Ansari, Ostrow School of Dentistry of USC, Los Angeles, CA

A. Moshaverinia, Ostrow School of Dentistry of USC, Los Angeles, CA

H. H. Zadeh, Ostrow School of Dentistry of USC, Los Angeles, CA

372

Engineered Microstructure Granules for Tailored Drug Release Rate

M. Hong, Columbia University Medical Center, New York, NY

D. S. Oh, Columbia University Medical Center, New York, NY

373

Drug Release and Mechanical Effects of Poly(β-Amino Ester) and Hydroxyapatite on In Situ Forming PLGA Systems

P. D. Fisher, University of Kentucky, Lexington, KY

T. Milbrandt, University of Kentucky, Lexington, KY

Z. Hilt, University of Kentucky, Lexington, KY

D. A. Puleo, University of Kentucky, Lexington, KY

374

Tailored Properties of Bilayered Calcium Sulfate and Calcium Phosphate Bone Graft Substitutes

B. Orellana, University of Kentucky, Lexington, KY

M. McQuinn, University of Kentucky, Lexington, KY

D. Puleo, University of Kentucky, Lexington, KY

375

Self-healing Colloidal Gels are formed by Cohesive Interactions between Gelatin and Hydroxyapatite Nanoparticles

S. C. G. Leeuwenburgh, Radboud University Medical Center, Nijmegen, Netherlands

M. Bongio, Radboud University Medical Center, Nijmegen, Netherlands

K. Farbod, Radboud University Medical Center, Nijmegen, Netherlands

J. J. J. van den Beucken, Radboud University Medical Center, Nijmegen, Netherlands

J. A. Jansen, Radboud University Medical Center, Nijmegen, Netherlands

376

Surface Adsorption of rhBMP-2 to Hydroxyapatite Reinforced PEEK Scaffolds

M. J. Meagher, University of Notre Dame, Notre Dame, IN

C. H. Merrill, University of Notre Dame, Notre Dame, IN

R. K. Roeder, University of Notre Dame, Notre Dame, IN

377

SrO and SiO2 Doped Tricalcium Phosphate bone tissue engineering Scaffolds with improved mechanical and biological properties

D. Ke, Washington State University, Pullman, WA

378

Multifunctional Neodymium Doped Hydroxyapatite Supramolecular Complexes as Luminescent Drug Carriers

S. P. Victor, Sree Chitra Tirunal Institute for Medical Science and Technology, Trivandrum, India

M. Jayabalan, Sree Chitra Tirunal Institute for Medical Science and Technology, Trivandrum, India

C. P. Sharma, Sree Chitra Tirunal Institute for Medical Science and Technology, Trivandrum, India

Engineering Biomaterial Surface Topography for Tissue Repair

380

Bone Bioactive Ceramic Coatings: The Synergistic Effects of Surface Roughness and Material Chemistry

. Aniket, Duke University, Durham, NC

R. Reid, University of North Carolina at Charlotte, Kannapolis, NC

I. Marriott, University of North Carolina at Charlotte, Charlotte, NC

A. El-Ghannam, University of North Carolina at Charlotte, Charlotte, NC

381

Mass Spectral Imaging for Analysis of Tissue Scaffolds

L. J. Gamble, University of Washington, Seattle, WA

D. Graham, University of Washington, Seattle, WA

382

Antibacterial Polyhydroxybutyrate (PHB) Membranes for Guided Bone Regeneration

B. Ercan, Northeastern University, Boston, MA

Z. Karahaliloglu, Northeastern University, Ankara, Turkey

T. Webster, Northeastern University,

383

Enhanced Osteoblastic Differentiation and Maturation by Titanium and Titanium-Zirconium Nanostructured and Hydrophilic Surface Modifications

E. Lotz, Virginia Commonwealth University, Richmond, VA

R. Olivares-Navarrete, Virginia Commonwealth University, Richmond, VA

S. Hyzy, Virginia Commonwealth University, Richmond, VA

S. Berner, Institut Straumann AG, Basel, Switzerland

Z. Schwartz, Virginia Commonwealth University, Richmond, VA

B. Boyan, Virginia Commonwealth University, Richmond, VA

384

Nanotopography-mediated Cell Filopodial Extension on Stiff Materials

L. Yang, Soochow University, Suzhou, China

Y. Lin, Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, Hong Kong

B. W. Sheldon, School of Engineering, Brown University, Providence, RI

385

Effect of Titanium Dioxide Nanotubes Dimensions on Prolonged Release of Drug Molecules

T. Shokuhfar, Michigan Technological University, Houghton, MI

A. Hamlekhan, Michigan Technological University, Chicago, IL

C. Sukotjo, University of Illinois at Chicago, Chicago, IL

A. Yarin, University of Illinois at Chicago, Chicago, IL

S. S. Ray, University of Illinois at Chicago, Chicago, IL

M. T. Mathew, Rush University, Chicago, IL

Molecular Mechanisms Governing Protein-Surface and Cell-Surface Interactions

386

A Strategy for Determining the Structure of Surface Bound Proteins

D. G. Castner, University of Washington, Seattle, WA

T. Weidner, Max Planck Institute for Polymer Research, Mainz, Germany

L. J. Gamble, University of Washington, Seattle, WA

387

Comparative Factor XII Contact Activation at Hydrophilic and Hydrophobic Surfaces and  Interactions with Prekallikrein and Factor XI

L. Xu, The Pennsylvania State University College of Medicine, Hershey, PA

S. Herron, Milligan College, Milligan College, TN

Y. Xu, Hershey High School, Hershey, PA

E. A. Vogler, Pennsylvania State University, University Park, PA

C. A. Siedlecki, Pennsylvania State University College of Medicine, Hershey, PA

388

A degradable polar hydrophobic ionic polyurethane attenuates IgG-Fab site-induced monocyte activation

K. Battiston, University of Toronto,

B. Ouyang, University of Toronto,

E. Honarparvar, University of Toronto,

R. Labow, University of Ottawa,

C. Simmons, University of Toronto,

P. Santerre, University of Toronto,

389

Determination of Orientation and Adsorption-Induced Changes in Tertiary Structure of Proteins on Material Surfaces by Chemical Modification and Peptide Mapping

A. A. Thyparambil, Clemson University, Clemson, SC

Y. Wei, Clemson University, Clemson, SC

R. A. Latour, Clemson University, Clemson, SC

390

Effect of materials properties of hydroxyapatite nanocrystals on fibronectin conformation

F. Wu, Cornell University, Ithaca, NY

D. D. W. Lin, Cornell University, Ithaca, NY

L. Estroff, Cornell University, Ithaca, NY

D. Gourdon, Cornell University, Ithaca, NY

391

Investigating the Role(s) of Cell Adhesion Molecules in Maintaining Human Pluripotent Stem Cells

J. W. Lambshead, CSIRO, Clayton, Victoria, Australia

C. O'Brien, CSIRO, Clayton, Victoria, Australia

L. Meagher, CSIRO, Clayton, Victoria, Australia

A. L. Laslett, CSIRO, Clayton, Victoria, Australia

392

Bio-Smart Surfaces Prepared by SET-LRP and Host-Guest Interaction

G. Chen, Soochow Unversity, Suzhou, China

X. Shi, Soochow University, Suzhou, China

H. Chen, Soochow University, Suzhou, China

393

An FVIII-derived Peptide Enables VWF-binding of an Artificial Platelet Substitute without Interfering with Natural Platelet Adhesion to VWF

C. L. Modery-Pawlowski, Case Western Reserve University, Cleveland, OH

H. Haji-Valizadeh, Case Western Reserve University, Cleveland, OH

A. Sen Gupta, Case Western Reserve University, Cleveland, OH

Targeting to Cellular and Pathological Microenvironments

395

Targeting Astrocyte Phenotypic Switch after Neural Injury

W. Marsh, Arizona State University, Tempe, AZ

S. E. Stabenfeldt, Arizona State University, Tempe, AZ

396

Fibrin-Binding, Peptide Amphiphile Micelles for Targeting Glioblastoma

E. Chung, The University of Chicago, Chicago, IL

Y. Cheng, The University of Chicago, Chicago, IL

R. Morshed, The University of Chicago, Chicago, IL

K. Nord, The University of Chicago, Chicago, IL

Y. Han, The University of Chicago, Chicago, IL

M. Wegscheid, The University of Chicago, Chicago, IL

B. Auffinger, The University of Chicago, Chicago, IL

D. Wainwright, The University of Chicago, Chicago, IL

M. S. Lesniak, The University of Chicago, Chicago, IL

M. Tirrell, The University of Chicago, Chicago, IL

397

Nanoengineered particles for enhanced intra-articular retention and delivery of therapeutic proteins

A. Singh, Cornell University, Ithaca, NY

R. Agarwal, Georgia Tech, Atlanta, GA

C. Diaz, Georgia Tech, Atlanta, GA

N. Willett, Georgia Tech, Atlanta, GA

P. Wang, USC, Columbia, SC

L. A. Lee, 4A&Q NanoDesigns, LLC, Columbia, SC

Q. Wang, USC, Columbia, SC

R. E. Guldberg, Georgia Tech, Atlanta, GA

A. J. Garcia, Georgia Tech, Atlanta, GA

398

Degradable Nanoparticles for pH-dependent Cytosolic Drug Delivery

J. M. Page, Vanderbilt University, Nashville, TN

B. Evans, Vanderbilt University, Nashville, TN

M. Gupta, Vanderbilt University, Nashville, TN

S. Guelcher, Vanderbilt University, Nashville, TN

C. Duvall, Vanderbilt University, Nashville, TN

399

Unnatural Killer Cells: TRAIL-Coated Leukocytes that Kill Cancer Cells in the Circulation

M. J. Mitchell, Cornell University, Ithaca, NY

E. C. Wayne, Cornell University, Ithaca, NY

K. Rana, Cornell University, Ithaca, NY

C. B. Schaffer, Cornell University, Ithaca, NY

M. R. King, Cornell University, Ithaca, NY

400

Ortho-hydroxy phenyl boronic acids rescue mice from lactic acidosis by increasing lactate metabolism

A. P. Acharya, University of California, Berkeley, Berkeley, CA