Society For Biomaterials
2015 Annual Meeting
Poster Presentations

Academic- Industry Collaborations in Biomaterials Research

500. Accelerated Thermoplastic Polyurethane Hydrolytic Stability Screening
D. K. Dempsey ¹ , N. Aumsuwan¹, H. Swen¹, J. Zupancich¹, P. Gray¹, T. Touchet², E. Cosgriff-Hernandez², C. P. Chawla ^1
1 DSM Biomedical, Berkeley, CA, ²Texas A&M University, Houston, TX

Accelerating Future Innovators

501. Reversible Dose-Based Drug Release Mediated by Azobenzene/α-Cyclodextrin Complexation to Study Myofibroblast Activation
E. M. Nehls , A. M. Rosales, K. S. Anseth
University of Colorado, Boulder, Boulder, CO

501A. Spatial and Temporal Interaction between Osteoprogenitors and Angioprogenitors on Composite Scaffolds
R. Rodriguez; L. Gaviria; A. Ong; T. Guda,
The University of Texas at San Antonio, San Antonio, TX

Advanced Antimicrobial Materials

502. Antimicrobial-tolerant bacterial biofilms are inhibited by Sharklet microtopography
E. E. Mann , M. C. Drinker, M. R. Mettetal, S. T. Reddy
Sharklet Technologies, Inc, Aurora, CO

503. Ultrasmall gold nanoparticles as bactericidal agents against planktonic and biofilm enveloped Staphylococci
S. K. Boda ¹ , U. Simon², B. Basu¹, W. Jahnen-Dechent ^3
1 Indian Institute of Science, Bangalore, India, ²Institute of Inorganic Chemistry, RWTH Aachen University, Aachen, Germany, ³Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany

504. Multifunctional Peptides for Infections Free Implant Surfaces
D. Khvostenko ¹ , K. Boone¹, S. VanOosten¹, D. Yucesoy², J. Ferracane³, H. Davis³, J. Mitchell⁴, P. Arnold⁵, C. Tamerler ^1
1 University of Kansas, Lawrence, KS, ²University of Washington, Seattle, WA, ³Oregon Health and Science University, Portland, OR, ⁴Midwestern University, Glendale, AZ, ⁵University of Kansas Medical Center, Kansas City, KS

505. Micro-Arc Oxidation Treatment for Improvement of Antibacterial Property of Titanium
Y. Tsutsumi ¹ , N. Niizeki², P. Chen¹, M. Ashida¹, H. Doi¹, K. Noda², T. Hanawa ^1
1 Tokyo Medical and Dental University, Tokyo, Japan, ²Shibaura Institute of Technology, Tokyo, Japan

506. Detachable Polymeric Films for Applications in Drug Delivery
S. Gates , A. Shukla
Brown University, Providence, RI

507. PEO-Tethered Peptides for Capture of Circulating Bacteria and Endotoxin in Sepsis
K. F. Schilke, R. Raman
Oregon State University, Corvallis, OR

508. Synthesis of Zwitterionic Sol-Gel Films to Prevent Bacterial Adhesion
H. Qu ¹ , R. Moya², P. Ducheyne ^1
1 University of Pennsylvania, Philadelphia, PA, ²Rice University, Houston, TX

509. WITHDRAWN

Advanced Hydrogels with Hierarchal Structures for Biological Applications

510. Hierarchical Macroporous Multifunctional Hydrogel Formation via Thermally-Induced Phase Separation for Neuronal Regeneration
S. Tang , B. Wing, E. Morin, S. Goddard, W. He
University of Tennessee, Knoxville, Knoxville, TN

511. PEG/Poly(acrylic acid) Semi-IPN Hydrogels for Post-Synthesis Electrostatic Antibiotic Loading and Controlled Release
Y. Wu, M. Libera
Stevens Institute of Technology, Hoboken, NJ

512. Chitosan-Containing Bioadhesive Hydrogels as Hemostatics
Y. Koyama , S. Yamaguchi, Y. Kurachi, M. Eriguchi, T. Ito
Japan Anti-tuberculosis Association, Shin-Yamanote Hospital, Tokyo, Japan

513. Characterization of a Multi-Functional Tetronic Surgical Adhesive Containing Chitosan for Soft Tissue Applications
L. Sanders , K. Webb, T. Mefford, J. Nagatomi
Clemson University, Clemson, SC

514. Robust Approaches to Interface External Tubing to Freestanding Microfluidic Hydrogels
S. Faley , B. Baer, T. Larsen, L. M. Bellan
Vanderbilt University, Nashville, TN

515. Photopatterning Hyaluronic Acid into Mechanically Robust Hydrogels Based on Melt-Assembled Networks of Sphere-Forming Block Copolymers
J. T. Lewis , T. S. Bailey
Colorado State University, Fort Collins, CO

516. Thermoreversible Scaffolds Improve Transient Three-Dimensional Culture by Facilitating Rapid Cell Recovery
J. M. Heffernan ¹ , D. J. Overstreet¹, S. Srinivasan¹, B. L. Vernon², R. W. Sirianni ^1
1 Barrow Neurological Institute, Phoenix, AZ, ²Arizona State University, Tempe, AZ

517. Enzyme Resistance and Mechanical Stability of Genipin-Crosslinked Films
A. Iftikhar , M. Cramer, C. Bettinger
Carnegie Mellon University, Pittsburgh, PA

518. High-Throughput Drop-Based Microfluidics to Prepare Stable Agarose Hydrogels
E. Davé ¹ , C. Muus², D. A. Weitz ^2
1 Harvard University, Hillsborough, NJ, ²Harvard University, Cambridge, MA

Advances in Programmable Biomaterials for Drug Delivery and Regenerative Medicine

519. PLGA-Porous Silicon Composite Microspheres: Optimization Insights of a Double Controlled Release Platform for Tissue Engineering Applications
L. Pandolfi ^1,2 , S. Minardi^1,3, F. Taraballi^1,4, L. Xaewu¹, E. Tasciotti ^1
1 Center for Regenerative Medicine, Houston Methodist Research Institute, Houston, Texas, Houston, TX, ²College of Materials Science and Optoelectronic technology, University of Chinese Academy of Science, Beijing, China, ³Bioceramics and Bio-Hybrid Materials, National Research Council of Italy – ISTEC, Faenza, Ravenna, Italy, ⁴Pain Therapy Service, University of Pavia-Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

520. Gamma Irradiation-Controlled Burst Release of Curcumin from Chitosan to Counteract Radiation Damage
R. Chauhan , M. J. Graves, B. Nunn, A. Akalkotkar, R. S. Keynton, P. A. Soucy, M. G. O'Toole
University of Louisville, Louisville, KY

521. Elastin-like Polypeptide Microspheres: A Stimuli-Responsive Vehicle for Controlled Drug Delivery
Aniket , N. Tang, J. Rosenberg, A. Chilkoti, D. Needham
Duke University, Durham, NC

522. Examination of Radio-opacity Enhancing Additives in Shape Memory Polyurethane Foams
A. C. Weems , J. E. Raymond, T. Gustavson, K. T. Wacker, B. Keller, K. L. Wooley, D. J. Maitland
Texas A&M University, College Station, TX

523. pH Responsive Nanoparticles-in-Microparticles System for Oral Delivery of siRNA
L. E. Strong , J. M. Knipe, N. A. Peppas
The University of Texas at Austin, Austin, TX

524. Self-Assembly of Heterochiral Peptides with Varied Sequence Patterns
A. Koyfman , R. Appavu, S. Sheller, J. Rudra
UTMB, Galveston, TX

525. Differential Rates of Oxanorbornadiene-Mediated Drug Tethering and Release from Thiolated Nanoparticles
A. Schudel, C. Higginson, M. Bellavia, M. Finn, S. N. Thomas
Georgia Institute of Technology, Atlanta, GA

Basic Science Progress and Clinical Applications of Multi-Functional Biomaterials: A Focus on Multi-Drug Biomaterials and Devices

526. Design, Fabrication and Functional Evaluation of Textile Packing Material for Tissue Debridement
Y. Fu ¹ , S. Tao², L. Wang³, M. W. King ^1
1 North Carolina State University, USA and Donghua University, Shanghai, China, Raleigh, NC, ²North Carolina State University, Raleigh, NC, ³Donghua University, Shanghai, China

Benchtop Models to Support Medical Device and Pharmaceutical Invention and Commercialization

527. Neck Impingement Testing of a Novel Hard on Hard Hip Bearing
D. Rister ¹ , A. Parikh ^2
1 Smith & Nephew, Cordova, TN, ²Smith & Nephew, Inc., Memphis, TN

528. Novel UKR Micromotion Assessment Method Utilizing Optical Measurement Techniques in Correlation with Finite Element Analysis
R. Davignon , A. Gopalakrishnan, G. Yildirim
Stryker Orthopaedics, Cedar Knolls, NJ

Biofabrication and Biomanufacturing in Tissue Engineering and Regenerative Medicine (TERM)

529. Effects of 3D Modeling Parameters on Dimensional Accuracy of 3D-Printed Anatomical Structure
K. Ogden ¹ , C. Aslan², G. Tillapaugh-fay¹, D. D. Diallo³, N. O. Ordway ^1
1 SUNY Upstate Medical University, Syracuse, NY, ²Syracuse University, Syracuse, NY, ³University of South Florida, Tampa, FL

530. Image-based Analysis of iPS-Derived 3D-Cardiac Myoblast Tissues Constructed by Cell Accumulation Technique
M. Seo ¹ , D. Takagi¹, Y. Amano², M. Matsusaki ^2
1 Ricoh Corporation, Yokohama, Japan, ²Osaka University, Suita, Osaka, Japan

531. Automatic Filter Layer-by-Layer Coating System for Construction of iPS-Derived 3D Tissues by Cell Accumulation Technique
D. Takagi ¹ , S. Kamono¹, Y. Amano², M. Matsusaki², S. Miyagawa², M. Akashi ^2
1 Ricoh company, Yokohama, Japan, ²Osaka University, Suita, Japan

532. Polymer-Based “Glue Scaffold” with Nanometer-Sized Extracellular Matrix Films for Tissue Engineering
N. Uchida¹, S. Sivaraman², N. Amoroso³, W. Wagner³, A. Nishiguchi⁴, M. Matsusaki⁴, M. Akashi⁴, J. Nagatomi ^2
1 University of Tokyo, Tokyo, Japan, ²Clemson University, Clemson, SC, ³University of Pittsburgh, Pittsburgh, PA, ⁴Osaka University, Osaka, Japan

533. Engineering Alginate as Bioink for Bioprinting
Y. Mei , J. Jia, D. J. Richards
Clemson University, Charleston, SC

534. Highly Moldable 3D Nanofibrous Elastomeric Scaffolds with Enhanced Mechanical Properties
S. Lee , W. Choi, J. Jang
Yonsei University, Seoul, Republic of Korea

535. 3D Printing of Bone-Templated Scaffolds
S. J. Fernando ¹ , J. A. Sterling², S. A. Guelcher ^3
1 Vanderbilt University School of Medicine, Nashville, TN, ²Veterans' Affairs Tennessee Valley Healthcare System, Vanderbilt University School of Medicine, Nashville, TN, ³Vanderbilt University, Department of Chemical and Biomolecular Engineering, Nashville, TN

536. Bioengineering an Artificial Ovary with 3D Printing
A. L. Rutz , M. M. Laronda, K. A. Whelan, T. K. Woodruff, R. N. Shah
Northwestern University, Chicago, IL

537. Perfusable 3D Microchannel Networks Made From Sacrificial Fibers Increase Cell Viability in Gelatin Scaffolds
X. Wang , S. Faley, B. Baer, D. Bird, L. M. Bellan
Vanderbilt University, Nashville, TN

538. Biofabrication of Tissue Constructs for Craniomaxillofacial Reconstruction
C. Kengla , Y. J. Seol, H. Kang, J. J. Yoo, A. Atala, S. J. Lee
Wake Forest University, Winston Salem, NC

539. Fabrication of Multi-Material Tissue Scaffolds via Additive Manufacturing
N. A. Chartrain , A. R. Schultz, M. Price, T. E. Long, C. B. Williams, A. R. Whittington
Virginia Polytechnic Institute and State University, Blacksburg, VA

540. Using Electric Fields to Introduce Pores in Bacterial Cellulose Scaffolds for Tissue Engineering
A. Rolong ¹ , P. Gatenholm², R. V. Davalos ^1
1 Virginia Tech, Blacksburg, VA, ²BC Genesis LLC, Blacksburg, VA

541. Exploring Methods for Controlling the Quality of Random and Aligned Electrospun Nanofibers
C. F. Rediguieri ¹ , P. A. De Bank², G. L. B. Araujo¹, T. J. A. Pinto ^1
1 University of São Paulo, São Paulo, Brazil, ²University of Bath, Bath, United Kingdom

542. Hybrid Scaffold-reinforced Extracellular Matrix Hydrogels for Cartilage Tissue Engineering
S. Sonnenberg
UNC at Chapel Hill and NC State University, Raleigh, NC

543. Development of 3D Printed Hydrogel Scaffold with Core-Shell Nanoparticles for Nerve Regeneration
S. Lee , W. Zhu, L. G. Zhang
George Washington University, Washington, DC

Bio-Inspired Cellular Microenvironments

544. In Vitro Tumor Intravasation Assays Using 3D-Human Blood- and Lymph-Capillary Models
A. Nishiguchi , M. Matsusaki, M. Akashi
Osaka University, Suita, Japan

545. Induction of Intrafusal Muscle Fibers from Human Satellite Cells and Their Innervations by Human Stem Cell-Derived Sensory Neurons
X. Guo ¹ , A. Colon¹, C. Martin¹, H. Vandenburgh², J. Hickman ^1
1 University of Central Florida, Orlando, FL, ²Brown University, Providence, RI

546. The Correlation Between Substrate Stiffness and TGF-β1-Induced Hepatic Stellate Cell Activation
J. Narang , C. Lemmon
Virginia Commonwealth University, Richmond, VA

547. High Throughput Screening Format Identifies Synthetic Mimics of Matrigel for Tubulogenesis Screening
E. H. D. Nguyen , W. T. Daly, D. G. Belair, N. N. Le, W. L. Murphy
University of Wisconsin-Madison, Madison, WI

548. Material Properties and Differentiation Potential of Collagen-II Based 3D Microbeads for Cartilage Tissue Engineering
R. Tiruvannamalai-Annamalai , D. Mertz, E. Daley, J. Stegemann
University of Michigan, Ann Arbor, MI

549. Effects of Preparation Condition of Tumor Cell-Derived Matrices on Chemoresistance
T. Hoshiba , M. Tanaka
Yamagata University, Yonezawa, Japan

550. Dynamic Topographical Imprinting of Cellular Substrates
M. Ali , J. B. Shear
The University of Texas at Austin, Austin, TX

551. High Resolution Silica Tissue Replica as Cell Culture Scaffold for the Differentiation of Human Mescenchymal Stem Cells
S. W. Tang ¹ , F. Lv², V. Leung², Y. W. Lam ^1
1 City University of Hong Kong, Hong Kong SAR, Hong Kong, ²The University of Hong Kong, Hong Kong

552. WITHDRAWN

Biologically Derived Materials from Natural Sources

553. Aligned 3D Amino Acid Nanofiber Biomaterials
B. Li , X. Wang
West Virginia University School of Medicine, Morgantown, WV

554. Engineered Collagen-Mimetic Proteins for Wound Healing
M. B. Browning , B. Russell, J. Rivera, M. Hook
Texas A&M Health Science Center Institute for Biosciences and Technology, Houston, TX

555. Modular Gelatin Hydrogels Formed by Orthogonal Thiol-ene Photochemistry for 3D Hepatocyte Culture
T. Greene ¹ , C. Lin ^2
1 Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Needham, IN, ²Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, IN

556. Mechanical-Stress Assisted Modulation of the Properties of Temperature-Responsive Cell Culture Surface
Y. Akiyama ¹ , M. Matsuyama², N. Takeda², M. Yamato¹, T. Okano ^1
1 Tokyo Women's Medical University, Tokyo, Japan, ²Waseda University, Tokyo, Japan

557. Bioactive Modification of End-functionalized Multi-arm Poly(ethylene glycol) Affects Macroscopic Properties and Cellular Behavior
J. Kim, S. M. Niedzielski, R. Singh, A. J. Putnam, A. Shikanov
University of Michigan, Ann Arbor, MI

558. Development of a Tissue Specific Acellular Extracellular Matrix for Intervertebral Disc Regeneration Using a Gentle Decellularization Process
R. A. Wachs ¹ , A. Hyyti¹, R. C. Cornelison², C. E. Schmidt ^1
1 University of Florida, Gainesville, FL, ²University of Texas at Austin, Gainesville, FL

559. Acellular Collagen-Hydroxyapatite Scaffolds Support Osteoinduction after Subcutaneous Ectopic Implantation
M. J. Meagher , H. E. Weiss-Bilka, D. R. Wagner, R. K. Roeder
University of Notre Dame, Notre Dame, IN

560. In vitro Cytocompatibility Study of Nanocellulose
L. Huang ¹ , Y. Lu², S. Ozcan², W. He ^1
1 The University of Tennessee, Knoxville, TN, ²Oak Ridge National Laboratory, Oak Ridge, TN

561. Optimization of Alginate Templated Polypyrrole Composites for Tissue Engineering Scaffolds
C. J. Wright ¹ , B. Zhang², C. Yore³, T. Pannell³, T. W. Hanks ^3
1 University of Washington Bothell, Bothell, WA, ²University of Wollongong, Wollongong, Australia, ³Furman University, Greenville, SC

562. Characterization of Chitosan and the Effects of Cleaning
J. D. Bumgardner
The University of Memphis, Memphis, TN

563. Decellualrized Cow-derived Diaphragm ECM Scaffold for Tissue Engineered Diaphragm
H. Yi , Y. Zhang
Wake Forest Institute for Regenerative Medicine, Winston Salem, NC

564. Diffusion-Reaction Models of Genipin Incorporation into Fibrin Networks
M. Cramer , A. Iftikhar, C. Bettinger
Carnegie Mellon University, Pittsburgh, PA

565. Fabrication of Biodegradable β-TCP Scaffolds Using Natural Biogenic Magnesian Calcite Skeletons
X. Zhang ¹ , L. Yang¹, L. Cao¹, W. Cui¹, Z. Guo², Y. Bai¹, R. Yang ^1
1 Institute of Metal Research, Chinese Academy of Sciences, Shenyang, China, ²Xijing Hospital, The Fourth Military Medical University, Xi'an, China

566. Electrospun Chitosan Fibers for Insulin Delivery
M. G. Lancina III , L. Xu, N. D. Sheybani, H. Yang
Virginia Commonwealth University, Richmond, VA

Biomaterials Education

567. Modeling Biomaterial Research for Middle School Science Teachers
C. Nelson ¹ , N. Bhattarai ^2
1 Kernodle Middle School, Greensboro, NC, ²North Carolina A&T State University, Greensboro, NC

568. Assessment Modality for Biomaterial Education Outreach to Improve Pedagogical Methods
C. J. Gehrmann , G. S. McGraw, G. Schreyack, J. A. Jennings
University of Memphis, Memphis, TN

569. Biomaterials Research Projects for Undergraduate Students: Exploring the Correlation between Silk Fibroin Protein Aggregation and Intrinsic Fluorescence
S. Alibeik , P. Valverde, C. Bennett
Wentworth Institute of Technology, Boston, MA

Biomaterials for Cardiovascular Regeneration

570. Inter-species Variation in the Decellularization of Aortic Valves
M. C. VeDepo ¹ , E. E. Buse², M. Armstrong², M. Detamore³, G. L. Converse², R. A. Hopkins ^2
1 University of Kansas & Children's Mercy Hospital, Kansas City, MO, ²Children's Mercy Hospital, Kansas City, MO, ³University of Kansas, Lawrence, KS

571. Mechanical and Biological Evaluation of Small Diameter Blood Vessels with Weft-Knitted and Electrospun Bilayer Structure
M. W. King
North Carolina State University, Raleigh, NC

572. Biomaterial Topography Promotes Endothelial Cell Migration via Disrupted VE-Cadherin Signaling
S. Mascharak ¹ , P. Benitez², S. Heilshorn ^2
1 Stanford University, Santa Cruz, CA, ²Stanford University, Stanford, CA

573. Stromal Cell-Derived Factor-1a Releasing Metallic Stent for Accelerated Re-endothelialization Mediated by Mobilization and Recruitment of Endothelial Progenitor Cells
S. N. Kang, Y. K. Joung, D. K. Han
Korea Institute of Science and Technology, Seoul, Republic of Korea

574. In Vivo Assessment of Engineered Cardiac Patches for Repairs of Congenital Heart Defects
J. G. Jacot
Rice University, Houston, TX

575. Functional Materials: Functionalization of Ultrabithorax Materials with Vascular Endothelial Growth Factor Enhances Primary Human Endothelial Cell Survival and Activation
D. W. Howell , C. Duran, S. Tsai, S. E. Bondos, K. J. Bayless
Texas A&M Health Science Center, College Station, TX

576. Preparation and Physical Properties of a Small Diameter Decellularized Vascular Graft Covered with Electrospun Fibers
T. Kimura ¹ , H. Morita¹, P. Wu¹, N. Nakamura¹, K. Nam¹, T. Fujisato², A. Kishida ^1
1 Tokyo Medical and Dental University, Tokyo, Japan, ²Osaka Institute of Technology, Osaka, Japan

Biomaterials for Regenerative Engineering

577. Human Recombinant Chimeric Protein COMP-Ang1 Promotes Angiogenesis and Bone Regeneration in a Rat Mandible Bone Defect Model
G. Bhattarai , S. B. Poudel, S. Kook, J. Lee
Chonbuk National University, School of Dentistry, Institute of Oral Bioscience, Jeonju, Republic of Korea

578. Engineered Polycaprolactone-Magnesium Hybrid Porous Scaffold for Bone Regeneration
K. W. K. Yeung ¹ , H. Wong¹, P. Chu², K. D. K. Luk¹, K. M. C. Cheung ^1
1 The University of Hong Kong, Hong Kong, Hong Kong, ²City University of Hong Kong, Hong Kong, Hong Kong

579. Mechanical Improvement of Hyaluronic Acid (HA) Hydrogels and Incorporation of Polyethylene Glycol (PEG)
H. Lee , S. Jeong, J. Baek, J. Song, H. Kim
Seoul National University, Seoul, Republic of Korea

580. PCL Reinforcement of a Mineralized Collagen-GAG Scaffolds for In Vivo Implantation
D. W. Weisgerber ¹ , K. Erning¹, C. Flanagan², S. Hollister², B. A. Harley ^1
1 University of Illinois at Urbana-Champaign, Urbana, IL, ²University of Michigan Ann Arbor, Ann Arbor, MI

581. Biodegradable Magnesium-Polymer Composite for Enhanced Corrosion Resistance and Mechanical Strength
D. Y. Shin , M. Kang, S. Kim, J. Song, H. Kim
Seoul National University, Seoul, Republic of Korea

582. Optimizing Mesenchymal Stem Cell Wound Healing Properties on Electrospun Silk with Selenium Nanoparticles
S. Chung ¹ , M. Stolzoff¹, P. Tran², B. Ercan¹, T. J. Webster ^3
1 Northeastern University, Boston, MA, ²University of Melbourne, Parkville, Australia, ³Northeastern University, King Abdulaziz University, Boston, MA

583. The Effect of Collagen Vitrigel Nanostructure on Stem Cell Derived Retinal Pigment Epithelial Maturation
X. Wang , J. Maruotti, J. Roman, H. Mao, D. J. Zack, J. H. Elisseeff
Johns Hopkins University, Baltimore, MD

584. Microporous Biopolymer Cell Carriers Prepared By Microfluidic Device for Tissue Engineering
J.H. Park, H.Y. Lee, C.M. Han, H.W. Kim
Dankook University, Cheonan, Republic of Korea

585. Magnetite-Doped Organic-Inorganic Nanocomposite Scaffolds Stimulate Bone Cell Functions
K. Dashnyam, J. Kim , M. Kim, R. Perez, E. Lee, S. Seo, H. Kim
Dankook University, Cheonan, Republic of Korea

586. Pegylated Poly(Ester Amide) Elastomers with Tunable Physico-Chemical, Mechanical and Degradation Properties
Y. Xue, A. Patel, V. Sant, S. Sant
University of Pittsburgh, Pittsburgh, PA

587. Feasibility of Novel Injectable Calcium Phosphate Cements Formulated with Bioactive Nanocomponent
S.-H. Shin , E.-F. Ahmed, R. Perez, D.-Y. Won, J.-H. Kim, S.-J. Seo, H.-W. Kim
Dankook University, Cheonan, Republic of Korea

588. Capturing Tissue Microenvironment on a Click-Chemistry Based Biodegradable Polymer Membrane
C. Wang ¹ , J. Yang², W. P. Yau¹, Y. W. Lam³, W. K. Yeung ^1
1 The University of Hong Kong, Hong Kong, ²The Pennsylvania State University, University Park, PA, ³City University of Hong Kong, Hong Kong

589. Decellularized Lung Extracellular Matrix Electrospun with Poly-L-Lactic Acid for Tissue Engineering
B. M. Young , R. A. Pouliot, B. A. Blakeney, B. P. Allen, G. E. Schreyak, R. L. Heise
Virginia Commonwealth University, Richmond, VA

590. Air-brushed Poly-DL-Lactic Acid Fiber Mats with Controllable Degradation for Tissue Engineering Applications
W. Tutak ¹ , A. Behrens², J. E. Seppala³, P. Kofinas ^2
1 ADA Foundation, Gaithersburg, MD, ²University of Maryland, College Park, MD, ³National Institute of Standards and Technology, Gaithersburg, MD

591. pH-Dependent Degradation of Poly(β-amino ester) Hydrogels
A. J. Chen , D. Puleo
University of Kentucky, Lexington, KY

Biomaterial-Tissue Interaction

592. Modeling of Chronic Ventral Hernia in Rabbit
G. T. Hilas ¹ , M. S. Taylor¹, T. A. Pruitt², J. T. Corbett ^1
1 Poly-Med, Inc., Anderson, SC, ²Godley-Snell Research Center, Clemson, SC

593. PLLA Coated WE43 Magnesium with a Hydroxyapatite Interlayer for Enhanced Adhesion and Corrosion Resistance
M. Kang , S. Kim, H. Kim
Seoul National University, Seoul, Republic of Korea

594. Clinical Biostability of Poly(carbonate urethane) Insulation in Neurostimulation Leads
G. Gallagher ¹ , C. Jenney ^2
1 St. Jude Medical, St. Paul, MN, ²St. Jude Medical, Sylmar, CA

595. Medical Device Retrieval Programme : an Indian initiative
J. Joseph ¹ , M. CV², V. Ramanathan², S. Arumugham², M. Mohanty ^2
1 VA Boston Health Care system, Harvard Medical School, Boston, MA, ²Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India

596. WITHDRAWN

597. Pore Formation Mediated by Polysaccharide Incorporation for 3D Skeletal Myotube Formation
M. Rich ¹ , M. K. Lee¹, N. Marshall¹, J. Chen¹, Z. Mahmassani¹, M. Boppart², H. Kong ^2
1 University of Illinois at Urbana-Champaign, Urbana, IL, ²University of Illinois, Urbana, IL

598. In Vivo Performance of Gellan Gum-Based Structures: A Comparison Study Between Hydrogels and Spongy-Like Scaffolds for Osteochondral Tissue Regeneration
R. F. Canadas, D. R. Pereira, J. Silva-Correia, C. Viegas, A. da Silva Morais, R. A. Sousa, A. P. Marques, R. L. Reis, J. M. Oliveira
3B's Research Group of University of Minho, Guimarães, Portugal

599. Controlling Nano-Ferrofluid Permeability with Surface Engineering and Their Future Applications
D. Shi ¹ , L. Sun², G. Mi², S. Bhattacharya³, S. Nayar³, T. Webster ^1
1 Northeastern University, Boston, MA, ²NEU, Boston, MA, ³Materials Science and Technology Division, CSIR-National Metallurgical Laboratory, Jamshedpur, India

600. Evaluation of Magnesium Alloys for Tracheal Stent Application
P. Saha ¹ , B. Lee¹, T. Yang¹, J. Waterman², T. Gilbert³, P. Hebda¹, P. Kumta ^1
1 University of Pittsburgh, Pittsburgh, PA, ²NC&AT, Greensboro, NC, ³Acell Inc, Columbia, MD

601. Development of a Semi-Laparoscopic Cecal Abrasion Model for Peritoneal Adhesions in a Rat
S. Mayes ¹ , S. Zawko¹, J. Ali², D. Peterson ^3
1 Alafair Biosciences, Austin, TX, ²UT Southwestern Austin, Austin, TX, ³Alafair Biosciences, Austin Brain and Spine, Austin, TX

602. Development of Tailored Bionanocomposites for Applications in Skin Tissue Regeneration
Y. S. Miranda Alarcón , A. M. Brown, I. A. Banerjee
Fordham University, Bronx, NY

603. Biocompatibility of the Intellirod System in an Ovine Posterior Lumbar Fusion Model
N. Russell ¹ , C. Christou¹, C. Tan¹, T. Wang¹, M. H. Pelletier¹, R. Eberle², W. R. Walsh ^1
1 Surgical and Orthopaedic Research Laboratories, UNSW Australia, Randwick, Australia, ²Intellirod Spine, Akron, OH

Biomimetic Materials for Tissue Engineering

604. Fluorenylmethyloxycarbonyl-based Peptide-Chitosan hybrid Scaffolds for Potential Applications in Cartilage Tissue Regeneration
S. M. Romanelli , G. A. Knoll, I. A. Banerjee
Fordham University, Bronx, NY

605. ECM-mimic Coating of Biopolymer Scaffolds to Promote Bone Regeneration
J.-E. Won , M.-H. Kim, H.-W. Kim
Institute of Tissue Regeneration Engineering (ITREN), Cheonan, Republic of Korea

606. Biomimetic Collagen-Phosphorylcholine Hydrogels as Corneal Implants for High Risk Patients
M. Islam ¹ , O. Buznyk², N. Pasyechnikova², M. Ljunggren³, K. Meek⁴, P. Lewis⁴, S. Hayes⁴, S. Iakymenko², J. Phopase³, E. Alarcon⁵, K. Merrett⁵, W. Liu⁶, P. Fagerholm³, M. Griffith ^3
1 Karolinska Institutet, Stockholm, Sweden, ²Filatov Institute of Eye Diseases & Tissue Therapy of the NAMS of Ukraine, Odessa, Ukraine, ³Linköping University, Linköping, Sweden, ⁴Cardiff University, Cardiff, United Kingdom, ⁵University of Ottawa, Ottawa, Canada, ⁶Tianjin University, Tianjin, China

607. Osteoblast Cellular Functions on Electron Beam Melting (EBM) Printed 3DTitanium Foam Structures as a Function of Porosity
K. Nune , D. Misra
University of Texas at El Paso, El Paso, TX

608. Interpenetrating Collagen-Fibrin Hydrogels for Skeletal Muscle Regeneration
S. Stagg ¹ , B. Pollot¹, C. R. Rathbone², A. Ong¹, T. Guda ^1
1 The University of Texas at San Antonio, San Antonio, TX, ²US Army Institute of Surgical Research, Ft. Sam Houston, TX

609. Poly(ε-caprolactone)/gelatin Composite Electrospun Scaffolds with Porous Crater-Like Structures for Tissue Engineering
P. T.J. Hwang , R. Huiszoon, J. NG, K. Murdock, G. Alexander, D. Lim, H. Jun
University of Alabama at Birmingham, Birmingham, AL

610. Characterizing Natural Hydrogel for Reconstruction of Three-Dimensional Lymphoid Stromal Network to Model T-Cell Interactions
J. Kim, B. Wu, S. Niedzielski, M. Hill, R. Coleman, A. Ono, A. Shikanov
University of Michigan, Ann Arbor, MI

611. Modulating MMP-2 Expression in HUVECs using PEG-conjugated Biomolecules
J. A. Hammer , R. M. Schweller, J. L. West
Duke University, Durham, NC

612. In Situ Forming Gelatin-Poly(Ethylene Glycol)-Tyramine Hydrogels via Dual Enzyme of Horseradish Peroxidase and Gluose Oxidase
B. Y. Kim, J. W. Bae, K. D. Park
Ajou University, Suwon, Republic of Korea

613. A Biomimetic Hydrogel Matrix Facilitates Evaluation of Cancer-associated Fibroblast Contributions to Tumor Angiogenesis
S. Ali , J. L. West
Duke University, Durham, NC

614. Adhesive Peptide Sequences Regulate Valve Interstitial Cell Phenotypes and Collagen Deposition
Y. Wu ¹ , K. J. Grande-Allen², J. L. West ^1
1 Duke University, Durham, NC, ²Rice University, Houston, TX

615. Perfusable Biomimetic Scaffolds within Microfluidic Devices
N. K. Virdone ¹ , N. A. Vera-Gonzalez¹, M. P. Cuchiara², J. L. West ^1
1 Duke University, Durham, NC, ²Rice University, Houston, TX

616. WITHDRAWN

617. Synthesis and Characterization of Chitosan Based Composite Scaffolds for Bone Tissue Engineering
U. Adhikari , N. Bhattarai
North Carolina A&T State University, Greensboro, NC

618. Optimizing Decellularization Detergents for Meniscus-Derived Injectable Hydrogel
J. Wu , Q. Ding, A. Dutta, Y. Hong
University of Texas at Arlington, Arlington, TX

619. Hydrogels with Gradient Niche Cues Enhance Cartilage Regeneration with Zonal Organization
F. Yang
Stanford University, Palo Alto, CA

620. Optimization of Skeletal Myocyte Expansion for Potential Use in Cell Therapy for Stress Urinary Incontinence
Y. Hu , Y. Zhang
Wake Forest Institute for Regenerative Medicine, Winston Salem, NC

621. Nano-hybrid Gel Scaffold for Biopharmaceuticals Delivery and Soft Tissue Engineering
H. Tan
Nanjing University of Science and Technology, Nanjing, China

Bio-Nanomaterials for Cancer Theranostic Treatment

622. Enhanced Radiation Therapy with Gold Nanoparticle-Loaded Multilayer Microdisks
A. D. Paro ¹ , P. Zhang², Y. Qiao³, J. Xia⁴, J. Guan⁴, L. Ma³, M. Su ^3
1 Northeastern University, Auburndale, MA, ²University of Maryland, College Park, College Park, MD, ³Northeastern University, Boston, MA, ⁴Florida State University, Tallahassee, FL

623. Synthesis of Cobalt Crosslinked Albumin Nanoparticles and In Vitro Evaluation of Macropinocytic Uptake in Gastric Carcinoma Cells
R. J. Cavazos, Jr.
University of North Texas, Denton, TX

624. Biodegradable Thermal-Responsive Dual-Imaging Enabled Nanoparticles
Z. Xie ¹ , P. Jadeja², J. U. Menon², D. Thakore², N. Pandey², J. Yang¹, K. T. Nguyen ^2
1 Penn State University, University Park, PA, ²UT Arlington, Arlington, TX

625. Preparation of Thermal/pH Dual Responsive Nanocarriers for Near Infrared Laser Guided Tumor Targeted Chemo/Photothermal Therapy
J. Chen , Y. Bi, H. Gao, A. Lan, Y. Hu
Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China

Biosensing and Complex Tissue Regeneration

626. Chemical Synthesis of Amine and Carboxyl Functionalized Polypyrrole Nanoparticles and Covalent Attachment of Antibody for Biosensing
J. Mao , Z. Zhang
Universite Laval, Quebec, QC, Canada

627. Functionalization of Gold Nanostars Sensors through Engineered Peptides for Bacterial Detection
H. Yazici , T. J. Webster
Northeastern University, Boston, MA

628. A New Method for Molecular Detection and Identification in a Metallic Nanopore
S. Bearden , G. Zhang
Clemson University, Clemson, SC

629. Active Microrheology of Magnetically-aligned Fibrin Gel to Measure Stiffness Anisotropy
M. Keating¹, S. Riemenschneider², E. Botvinick¹, R. Tranquillo ^2
1 UC-Irvine, Irvine, CA, ²Univ. Minnesota, Minneapolis, MN

630. Biocompatibility Evaluation of Skin-Wearable Silver Nanowire Based Hydration Sensors
M. G. McCord
North Carolina State University, Raleigh, NC

Carbon Nanomaterials

631. 3D-Printed High-Content Graphene Composites for Tissue Engineering
R. N. Shah ¹ , A. E. Jakus¹, A. L. Rutz¹, S. W. Jordan ^2
1 Northwestern University, Simpson Querrey Institute for BioNanotechnology, Chicago, IL, ²Northwestern University, Chicago, IL

632. ATP-Responsive Hybrid DNA/Graphene Nanoassemblies for Anticancer Drug Delivery
W. Sun , R. Mo, T. Jiang, Z. Gu
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695, USA, Center for Nanotechnology in Drug Delivery and Division of Molecular, Pharmaceutics Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Raleigh, NC

Cardiovascular Biomaterials

633. Cellular responses of smooth muscle cell to zinc ion
J. Ma , N. Zhao, D. Zhu
North Carolina Agricultural and Technical State University, Greensboro, NC

634. The Effects of Extracellular Magnesium Ion on Smooth Muscle Cells
J. Ma , N. Zhao, D. Zhu
North Carolina Agricultural and Technical State University, Greensboro, NC

635. Recapitulation of Myocardial Infarction Coupled with Patient-Specific iPSC-Derived Cardiomyocytes for Characterization of Chromosomal Mutation 9p21
A. Kumar ¹ , K. P. Tenerelli¹, W. Ferguson², V. Lo Sardo², K. K. Baldwin², E. J. Topol², A. J. Engler ^1
1 University of California, San Diego, La Jolla, CA, ²The Scripps Research Institute, La Jolla, CA

636. Biodegradable Polymer-Coated Drug-Eluting Stents with Improved Coating Stability Using Biodegradable Nano-Brushes
T. M. I. Bedair, Y. Cho, Y. K. Joung, D. K. Han
Korea Institute of Science and Technology, Seoul, Republic of Korea

637. Impacts of Manufacturing Processes and Temperature on the Water Absorption of a Siloxane-Based Polyurethane
G. Gallagher ¹ , C. Jenney ^2
1 St. Jude Medical, St. Paul, MN, ²St. Jude Medical, Sylmar, CA

638. Performance of OptimTM Insulation in an Accelerated In Vitro Model of Environmental Stress Cracking
A. Padsalgikar¹, G. Gallagher², E. Tkatchouk³, C. Iacob⁴, J. Runt ^4
1 St. Jude Medical, Rogers, MN, ²St. Jude Medical, St. Paul, MN, ³St. Jude Medical, Sylmar, CA, ⁴Penn State University, University Park, PA

639. Image Modalities to Visualize Polyester Fabric in Endovascular Stent Grafts
T. Yao ¹ , K. Mathews¹, I. Robertson¹, D. S. Lalush², L. W. Tse³, G. Soulez⁴, M. W. King ^1
1 North Carolina State University, Raleigh, NC, ²North Carolina State University and University of North Carolina at Chapel Hill, Raleigh, NC, ³Toronto General Hospital, University of Toronto, Toronto, ON, Canada, ⁴Université de Montréal, Montreal, QC, Canada

640. Characterization and Preparation of Bio-Tubular Scaffolds for Fabricating Artificial Vascular by Combining Electrospinning and 3D Printing System
S. J. Lee ¹ , D. N. Heo¹, Su A Park², I. K. Kwon ^1
1 School of Dentistry, Kyung Hee University, Seoul, Republic of Korea, ²Korea Institute of Machinery and Materials, Daejeon, Republic of Korea

641. Suppression of Abdominal Aortic Aneurysms Using Targeted Nanoparticles That Deliver an MMP Inhibitor
A. N. Chowdhury , N. Nosoudi, N. Vyavahare
Clemson University, Clemson, SC

642. Heparin-Mimicking Reverse Thermal Gel for the Treatment of Myocardial Ischemia
M. Laughter
University of Colorado at Denver, highlands ranch, CO

643. Microporous Textured Exterior Biointerface Prevents Stenosis in Arteriovenous Grafts
A. J. Marshall , A. Oda, B. Scanlan, M. G. Maginness
Healionics Corporation, Seattle, WA

Cells and Their Microenvironment: Translational Sciences

644. Pulsed Electrical Stimulation Activates Fibroblast Migration, Collagen Contraction, A-Smooth Muscle Actin Expression and Smad 2/3 Phosphorylation
M. Rouabhia ¹ , Z. Zhang ^2
1 University Laval, Québec, Canada, ²Laval University, Quebec, Canada

645. Anisotropy Increases Myogenic Regulatory Factors and Regenerates Skeletal Muscle
M. J. McClure ¹ , D. J. Cohen¹, Y. C. Huang², M. Sunwoo², B. D. Boyan¹, B. D. Boyan³, Z. Schwartz¹, Z. Schwartz ^4
1 Virginia Commonwealth University, Richmond, VA, ²Musculoskeletal Transplant Foundation, Edison, NJ, ³Georgia Institute of Technology, Atlanta, GA, ⁴The University of Texas Health Sciences Center at San Antonio, San Antonio, TX

Ceramics and Composites in Bone Tissue Engineering and Drug Delivery

646. Effect of Crystal Lattice Modification of a-Cristobalite on Drug Adsorption and Release Kinetics
C. J. Trujillo , A. El-Ghannam
University of North Carolina at Charlotte, Charlotte, NC

647. Development of Standardized Test Method for Evaluation of Nano-Crystalline Hydroxyapatite Forming Ability of Orthopedic, Dental and Craniofacial Device Materials
S. Brittain , P. Petrochenko, A. Kaiser, J. Johnson, L. Lo, J. Moreno, G. Kumar, A. Kaiser
US Food and Drug Administration, Silver Spring, MD

648. Inkjet-printed alumina pattern for improvement of the activity of Periodontal Ligament Cells
J. Kang ¹ , M. Lee¹, W. Seo¹, S. W. Lee², H. Choi ^3
1 Korea Institute of Ceramic Engineering & Technology, Seoul, Republic of Korea, ²Kyung Hee University, Seoul, Republic of Korea, ³ Yonsei University, Seoul, Republic of Korea

649. Effect of Coating and Pre-coating Techniques on the Compressive Strength of Fluorapatite Glass-ceramic Scaffolds
O. Goudouri , J. Harless, I. Denry
University of Iowa College of Dentistry, Iowa city, IA

650. Hydroxyapatite-PLGA-collagen Biomaterial for Bone Regeneration
D. B. Bhuiyan¹, R. Tannenbaum², J. C. Middleton³, T. Wick ^1
1 University of Alabama at Birmingham, Birmingham, AL, ²Stony Brook University, Stony Brook, NY, ³Tolmar Inc., Fort Collins, CO

651. MgO Nanoparticles Enhance Cell Functions and Reduce the Adhesion of Staphylococcus Aureus on Hydroxyapatite-PLLA Nanocomposites for Orthopedic Tissue Engineering Applications
D. J. Hickey , T. J. Webster
Northeastern University, Boston, MA

652. Fabrication and Characterization of Collagen/Apatite Scaffolds with Intrafibrillar Mineralized Collagen Fibers
M. Wei
Institute of Materials Science, Mansfield, CT

653. Cell Activity on the Alumina Microgroove Fabricated by Micro-Molding Process
J. Kang ¹ , S. Kim¹, M. Lee¹, W. Seo¹, S. W. Lee ^2
1 Korea Institute of Ceramic Engineering and Technology, Seoul, Republic of Korea, ²Kyung Hee University, Seoul, Republic of Korea

654. Poly (octanediol citrate)/Gallium-containing Bioglass Microcomposite Scaffolds
E. Zeimaran ¹ , S. Pourshahrestani¹, I. Djordjevic¹, B. P. Murphy¹, N. A. Kadri¹, M. R. Towler ^2
1 University of Malaya, Kuala Lumpur, Malaysia, ²Ryerson University, Toronto, Canada

655. In-Vivo Performance of a Novel Bioabsorbable Suture Anchor in a Rabbit Femoral Model
O. Ortiz , K. Lahteenkorva
ConMed, Largo, FL

Characterization of Microenvironment of Immune Cells in Wound Healing

656. M(IL-4) and M(IL-10) Induced Alterations in Gene and Protein Profiles of Rodent Wound Macrophages
G. Bajpai, J. M. Durdik, J. Stenken
University of Arkansas, Fayetteville, AR

Delivery of Nucleic Acids and Other Molecules that Modulate Gene Expression

657. DNA Complex Release System by Injectable Auto-Forming Alginate Gel Including Amorphous Calcium Phosphate
T. Ito ¹ , Y. Koyama ^2
1 Meiji Pharmaceutical University, Tokyo, Japan, ²Japan Anti-tuberculosis Association, Shin-Yamanote Hospital, Tokyo, Japan

658. Combinatorial Library of Ternary Polyplexes Enables Identification of Improved siRNA Nano-Formulations
T. A. Werfel , M. Miteva, C. Duvall
Vanderbilt University, Nashville, TN

659. Surface Mediated Polymer Electrolyte and Nanostructured Calcium Phosphate Composite (NanoCaPs) Layers: Novel Approach to Non-Viral Gene Delivery
S. Shekhar , A. Roy, P. N. Kumta
University of Pittsburgh, Pittsburgh, PA

660. Engineered RNA Nanorings for Efficient Delivery of siRNA
A. Koyfman ¹ , K. Afonin², A. Martins², E. Freed², W. Chiu³, J. Rudra¹, B. Shapiro ^2
1 University of Texas Medical Branch, Galveston, TX, ²National Cancer Institute, Frederick, MD, ³Baylor College of Medicine, Houston, TX

661. WITHDRAWN

662. One-pot Synthesis of Functional Poly(amino ester sulfide)s and Utility in Delivering pDNA and siRNA
D. Siegwart , Y. Yan, L. Xue, J. Miller
University of Texas Southwestern Medical Center, Dallas, TX

Dental/Craniofacial

663. Comparison of Electrospun and Lyophilized Gelatin + Chitin Whisker + Honey Membranes for Enhanced Periodontal Regeneration
A. E. Fetz ¹ , I. A. Rodriguez¹, B. W. Burger², G. L. Bowlin ^1
1 The University of Memphis, Memphis, TN, ²Dulles Institute for Oral/Maxillofacial Surgery, Sterling, VA

664. Application of Stem Cells Derived from the Periodontal Ligament or Gingival Tissue Sources for Tendon Tissue Regeneration
S. Ansari , X. Xu
USC, Los Angeles, CA

665. Composition Changes according to the Manufacturing Method of Dental Alloy Powder for Application of Selective Laser Melting System
H. Lee , C. Lee, M. Kim, C. Lee, H. Kim
National Institute of Food and Drug Safety Evaluation, Cheongju-si, Chungcheongbuk-do, Republic of Korea

666. Observed of Change in the Hardness of Ni-Cr alloy used to Dental Selective Laser Melting System
S. Choi , M. Hong
Catholic University of Pusan, Busan, Republic of Korea

667. Evaluation of the Effect of Early Bacterial Colonizers on the Surface of Retrieved Dental Healing Abutments
S. Sridhar ¹ , I. M. Gindri¹, P. Valderrama², T. G. Wilson, Jr.², D. C. Rodrigues ^1
1 University of Texas at Dallas, Richardson, TX, ²Private practice of Periodontics, Dallas, TX

668. Cathepsin-K Targeting Nanotherapeutics for Regenerative Repair of Abdominal Aortic Aneurysms
B. Jennewine , A. Ramamurthi
Cleveland Clinic, Cleveland, OH

669. Preparation of Decellularized Mandible Bone with Periodontal Membrane for Periodontal Reconstruction
N. Nakamura ¹ , A. Ito¹, K. Nam¹, T. Kimura¹, T. Fujisato², T. Tsuji³, A. Kishida ^1
1 Tokyo Medical and Dental University, Tokyo, Japan, ²Osaka Institute of Technology, Osaka, Japan, ³RIKEN, Kobe, Japan

670. Correlation between Rheological Behavior and Adhesion Properties of Denture Adhesives
N. Roohpour
Glaxosmithkline consumer health care, Weybridge, United Kingdom

Drug Delivery

671. Nanogels of Hydrophobized Methylcellulose
M. Jamard , T. R. Hoare, H. Sheardown
McMaster University, Hamilton, Canada

672. Characterization of Crosslinked Gelatin Microspheres for Controlled Growth Factor Delivery
P. A. Turner , J. P. Stegemann
University of Michigan, Ann Arbor, MI

673. Halloysite Nanotubes with Polyelectrolyte Nano-coatings Embedded with Rifampicin
W. R. Grimes Jr. , D. K. Mills
Louisiana Tech, Ruston, LA

674. Combinatorial Therapy of Rolipram and pNGF for Traumatic Brain Injury
C. Macks ¹ , S.-J. Gwak², G. Temples², G. Korneva³, J. Lee ^2
1 Clemson Univeristy, Duncan, SC, ²Clemson University, Greenville, SC, ³Clemson University, Clemson, SC

675. Ricinoleic acid Encapsulation into Liposomal Matrix for cutaneous Application
A. A. A. Nada , R. A. Abd EL Azeem
National research centre, Dokki, Giza, Egypt

676. Incorporation of Protein-based Therapeutic Agents into Coaxial Electrosprayed Particles for Cardiac Regeneration
M. Zamani ¹ , M. P. Prabhakaran², E. S. Thian¹, S. Ramakrishna ^1
1 Department of Mechanical Engineering, National University of Singapore, Singapore, Singapore, ²Center for Nanofibers and Nanotechnology, Nanoscience and Nanotechnology Initiative, Faculty of Engineering, National University of Singapore, Singapore, Singapore

677. Combination of Cold Atmospheric Plasma and Nanoparticles Drug Delivery toward More Efficient Breast Cancer Therapy
W. Zhu , S. Lee, M. Keidar, L. G. Zhang
The George Washington University, Washington, DC

678. Controlled Release of Ophthalmic Therapeutics from Injectable, Resorbable Copolymer Scaffolds
G. Prosperi-Porta , B. Muirhead, H. Sheardown
McMaster University, Hamilton, ON, Canada

679. Cell Membrane-mimetic Polymeric Micelles as Carriers for Drug Delivery
G. Liu ¹ , Y. Wang ^2
1 Sichuan University, Chengdu, China, ²National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China

680. Smart Hyperthermia Nanofiber Meshes With ‘On-Off’ Drug Release For Cancer Therapy
M. Ebara ¹ , E. Niiyama¹, K. Uto¹, C. M. Lee², T. Aoyagi ^1
1 National Institute for Materials Science (NIMS), Tsukuba, Japan, ²Osaka University Hospital, Suita, Japan

681. Hydroxyapatite-Calcium Sulfate Biphasic Microspheres as a Growth Factor Carrier for Sustainable Release
J. Baek , J. Song, H. Kim
Seoul National University, Seoul, Republic of Korea

682. Resorbable Bioactive Antimicrobial Implant for Bone Regeneration
A. El-Ghannam ¹ , k. A. Aly Ahmed ^2
1 University of North Carolina at Charlotte, Charlotte 28223 USA, Charlotte, NC, ²Aljouf Unversity, KSA, Aljouf, Saudi Arabia

683. PLGA/Chitosan based Composite Microspheres for Drug Delivery
S. Rahman , N. Bhattarai
North Carolina A&T State University, Greensboro, NC

684. An Accelerated Release Study to Evaluate Long-acting Levonorgestrel Contraception Dosage Forms
L. Wang , T. Lowe
University of Tennessee Health Science Center, Memphis, TN

685. The Effect of Induced Cell Alignment on the Endocytosis of Nanoparticles
P. Fattahi ¹ , P. J. Butler², J. L. Brown ^2
1 The Pennsylvania State University, State College, PA, ²The Pennsylvania State University, University Park, PA

686. Characterization of Pentagalloyl glucose (PGG) loaded BSA nanoparticles as targeted therapy for abdominal aortic aneurysm (AAA) regression
N. Nosoudi , A. Chowdhury, N. Vyavahare
Clemson University, Clemson, SC

687. Synthesis and Characteristics of PEI-based Copolymers and Nanoparticles for Potential Gene Delivery Applications
C. Liu , M. Wang
The University of Hong Kong, Hong Kong, Hong Kong

Drug Delivery for Immunomodulation

688. Negatively Charged MRI Nanoprobes for Dendritic Cell Labeling and in Vivo Tracking
H. Ai , C. Wu
National Engineering Research Center for Biomaterials, Sichuan University, China, Chengdu, China

689. Delivery of Indoleamine 2,3 Dioxygenase for the Induction of Immune Tolerance
E. Bracho-Sanchez , A. Hassanzadeh, J. S. Lewis, B. G. Keselowsky
University of Florida, Gainesville, FL

690. In Vivo Macrophage Activation via Locally Delivered Dexamethasone
G. Keeler, J. Durdik, J. Stenken
University of Arkansas, Fayetteville, AR

691. Macrophage Response to Chitosan/Poly-(γ-Glutamic acid) Nanoparticles Carrying an Anti-Inflammatory Drug
R. M. Gonçalves , A. C. L. Pereira, I. O. Pereira, M. J. Oliveira, M. A. Barbosa
Institute of Biomedical Engineering (INEB), Porto, Portugal

692. Less Phagocytosis of Biotinylated Polymeric Prodrug Micelles Using CD47-Streptavidin Fusion Protein
A. Sawdon
Michigan Tech, Houghton, MI

693. Tobramycin and Vancomycin Release from Local Delivery Devices
C. M. Wells
University of Memphis, Memphis, TN

Engineering Cells and Their Microenvironments

694. Dynamically Stiffening Hydrogels Differentially Modulates Malignant Transformation of Mammary Epithelial Cells
S. Wei , J. Yang, A. Engler
UC San Diego, San Diego, CA

695. Characterizing Effects of Microenvironments on Mechanical Properties of Cardiac Microtissues
A. Desai ¹ , D. Dean ^2
1 Clemson University, Greenville, SC, ²Clemson University, Central, SC

696. Heparin Cell Coating Effects on Cell Number During Mesenchymal Stem Cell Aggregate Culture with FGF-2
J. Lei , E. Trevino, J. S. Temenoff
Georgia Tech, Atlanta, GA

Engineering Tissue Interfaces

697. The Evaluation of Gold and Hydroxyapatite Nano-grafts in a Green Fluorescent Protein Porcine Model
S. E. Smith , R. White, D. Grant, S. Grant
University of Missouri, Columbia, MO

698. In Vitro Evaluation of Osteogenic Activity of Human Adipocyte Derived Stem Cells on Varied Scaffold Formulations
A. V. Janorkar , P. Bierdeman, B. Gurumurthy
University of Mississippi Medical Center, Jackson, MS

699. Tissue Regeneration of Tendon-Bone Junction: Evaluation of the Role of TgfbR2 Expressing Progenitor Cells on Multiphase Resorbable Braided Scaffolds
H. Ramakrishna ¹ , T. He¹, T. Li², J. Temple², A. Spagnoli², M. King ^1,3
1 North Carolina State University, Raleigh, NC, ²University of North Carolina, Chapel hill, NC, ³College of Textiles, Donghua University, Shanghai, China

700. Reconfigurable Substrate Topography for Tracking Cell Dynamics
P. Pholpabu , C. Bettinger, A. Balasubramanian, S. Kustra, H. Wu
Carnegie Mellon U, Pittsburgh, PA

Hands-On Biomaterials Research

701. Residual Volatiles Quantification for Novel Matrices
C. Culbreath , S. McCullen, C. Fitzwater, J. Corbett
Poly-Med, Inc., Anderson, SC

702. Compositional Changes in vitro for Two Glycolide Based Copolymers
D. R. Ingram , J. T. Corbett, M. S. Taylor, S. D. McCullen
Poly-Med, Inc., Anderson, SC

703. Building Scientific Confidence in BME Undergraduates via Inquiry-guided Biomaterials Laboratory
S. E. Stabenfeldt , C. Ankeny
Arizona State University, Tempe, AZ

704. Development of a 3-week Intensive Interdisciplinary Biomaterials Course for Non-engineering Majors
C. J. Wright ¹ , V. L. Turgeon ^2
1 University of Washington Bothell, Bothell, WA, ²Furman University, Greenville, SC

Harnessing Biomaterials to Engineer the Adaptive Response for Immunity or Tolerance

705. Immobilizing CD47 Polypeptide on Implantable Biomaterials
C. M. EVARO ¹ , B. E. MITCHELL¹, Z. GU², M. W. KING ^3
1 North Carolina State University, Raleigh, NC, ²North Carolina State University and University of North Carolina at Chapel Hill, Raleigh, NC, ³North Carolina State University and Donghua University, Shanghai, China, Raleigh, NC

High-Throughput Methods to Control Cell Behavior

706. Microwell arrays for high-throughput investigation of multi-species biofilm formation
R. Hansen , C. Timm, S. Retterer
Oak Ridge National Laboratory, Oak Ridge, TN

707. Engineering Hydrogels with Dual Gradients of Mechanical and Biochemical Cues to Decipher Stem Cell-Niche Interactions
X. Tong , J. Jiang, D. Zhu, F. Yang
Stanford University, Stanford, CA

708. Electrospun Photoclickble Thio-ene Poly(ethylene glycol) Hydrogel Microarrays for Stem Cell Fate Optimization
S. Sharma , M. Floren, W. Tan, S. Bryant
University of Colorado Boulder, Boulder, CO

Injectable Biomaterials for Tissue Regeneration

709. Composite Hydrogel Scaffold for Increased Fat Retention after Surgical Graft Procedure
C. M. Mahoney , D. Minteer, K. G. Marra, P. Rubin
University of Pittsburgh, Pittsburgh, PA

710. Injectable Hydrogel based on Supramolecular Inclusion Complexes between Alginate-graft-Cyclodextrin and Polypropylene Glycol
T. Miao , S. L. Fenn, P. N. Charron, R. A. Oldinski
University of Vermont, Burlington, VT

711. Degradation and Cell Survival in a Fast-Degrading Thio-Acrylate based Hydrogel
A. Emmakah ¹ , C. Lin², T-M. G. Chu ^3
1 Purdue University, Indianapolis, IN, ²Indiana University-Purdue University at Indianapolis, Indianapolis, IN, ³Indiana University School of Dentistry, Indianapolis, IN

712. Injectable Enzymatically Crosslinked Hydrogels: A Unique Platform with Tunable Degradation Properties
S. V. Gohil ¹ , A. Padmanabhan², L. Nair ^1
1 Uconn Health, Farmington, CT, ²UConn, Storrs, CT

713. Development of a Novel Injectable Alginate-Collagen-Apatite Hydrogel for Bone Tissue Regeneration
S. Bendtsen, M. Wei
University of Connecticut, Storrs, CT

714. A Hydrogel for Local T Lymphocyte Delivery towards Enhanced Cancer Immunotherapies
C. Ceccaldi ¹ , A. Monette², E. Assaad¹, R. Lapointe², S. Lerouge ^1
1 Laboratory of Endovascular Biomaterials (LBeV), École de technologie supérieure (ETS)/ CHUM Research Center (CRCHUM), Montréal, QC, Canada, Montréal, QC, Canada, ²Laboratoire d'Immuno-Oncologie, ICM, U de Montréal/CRCHUM, Montréal, QC, Canada, Montréal, QC, Canada

715. Shear Strength of Thermogelling Scaffold for Intervertebral Disc (IVD) Tissue Engineering
T. Mauriello, T. Christiani, P. Myers, D. Collins, A. Nitzl, E. England, C. Iftode, J. Kadlowec, A. J. Vernengo
Rowan University, Glassboro, NJ

716. Mechanically Enhanced Hyaluronic Acid-Based Hydrogels via Dual-Crosslinking Process
J. Song , H. Kim
Seoul National University, Seoul, Republic of Korea

717. Preparation of Poly(Ethylene Glycol)-B-Polyester Block Copolymers with Zwitterionic End Group for Thermo-Responsive Properties
J. H. Park ¹ , D. Y. Kwon¹, B. K. Lee¹, C. H. Kim², M. S. Kim ^1
1 Ajou University, Suwon, Republic of Korea, ²Korea Institue of Radiological and Medical Sciences, seoul, Republic of Korea

718. In vitro and in vivo Evaluation of Chitosan-Sotradecol Hydrogel, An Embolizing Sclerosing Agent for the Treatment of Endoleaks
F. Zehtabi ^1,2 , A. Fatimi¹, A. Bertrand-Grenier¹, G. Soulez¹, S. Lerouge ^1
1 CHUM Research Center (CRCHUM), Montréal, QC, Canada, Montreal, QC, Canada, ²École de Technologie Supérieure (ETS), Montreal, QC, Canada

719. Electrospinning of Alginate Micro-Beads
N. Bhattarai , N. Rijal, R. Roman
North Carolina A&T State University, Greensboro, NC

720. Injectable Thermosensitive Chitosan Hydrogels with Enhanced Properties
E. Assaad , M. Maire, S. Lerouge
École de technologie supérieure, Montreal, QC, Canada

721. Extracellular Matrix Hydrogels from Decellularized Lung Tissue
R. A. Pouliot , N. S. Mikhaiel, B. Wong, R. L. Heise
Virginia Commonwealth University, Richmond, VA

Innate Immunity and Inflammation in Biomaterials Contexts

722. Macrophage Polarization in Response to Self-Assembling Peptides
R. De Loera , Y. Vigneswaran, J. Collier
University of Chicago, Chicago, IL

723. Material-Modulated Polymorphonuclear Leukocyte Degranulation Affects Monocyte Adhesion on Endothelial Cells Under Shear Stress
T. J. Lieberthal , H. C. Cohen, J. Kao
University of Wisconsin-Madison, Madison, WI

724. In Vivo Effect of Locally-Delivered Modulators on Cytokine Production and Macrophage Activation
K. Alkhatib ¹ , G. D. Keeler², T. M. Poseno², J. M. Durdik², J. A. Stenken ^2
1 University Of Arkansas, Bentonville, AR, ²University of Arkansas, Fayetteville, AR

725. Age-Related Changes in Macrophage Response to ECM Biomaterials|
S. T. LoPresti ¹ , S. Patil², S. Dash¹, S. Bowers¹, L. Zhang¹, C. L. Dearth³, B. N. Brown ^1
1 University of Pittsburgh, Pittsburgh, PA, ²Allegheny Community College, Pittsburgh, PA, ³Walter Reed National Military Medical Center, Bethesda, MD

Local Delivery of Drugs and Growth Factors from Implant Coatings

726. Control of PLL/HA Multilayer Film Formation via Crosslinkable Hyaluronic Acid Derivatives: The Differences between Fast (Tyramine) and Slow (Aldehyde) Crosslinking Moieties
H. Knopf-Marques ¹ , L. Wolfowa², S. Singh³, V. Velebny², P. Schaaf¹, A. Ghaemmaghami³, N. E. Vrana⁴, P. Lavalle ^1
1 INSERM UMR 1121, Strasbourg, France, ²Contipro Biotech S. R. O, Dolni Dobrouc, Czech Republic, ³School of Life Sciences, University of Nottingham, Nottingham, United Kingdom, ⁴PROTIP MEDICAL, Strasbourg, France

727. Surface Modification of CoCr alloy Using Vitamin-E for Cardiovascular Stents
E. Thiruppathi¹, J. Anderson¹, M. Larson², G. Mani ^1
1 University of South Dakota, Sioux Falls, SD, ²Augustana College, Sioux Falls, SD

728. Model for Drug Partitioning in AEMA Containing Poly(HEMA)-based Hydrogels using Coomassie Brilliant Blue
R. Idziak¹, C. Kotanen¹, R. Sullivan¹, A. M. Wilson², D. R. Janagam³, T. L. Lowe³, A. Guiseppi-Elie ^1
1 Clemson University, Clemson, SC, ²University of the West Indies, St. Augustine, Trinidad and Tobago, ³University of Tennessee Health Science Center, Memphis, TN

729. Biodegradable antibiotic-releasing implant coatings to prevent orthopaedic implant infections
A. A. Ashbaugh , J. Shahbazian, L. Miller, H. Mao
Johns Hopkins University, Baltimore, MD

730. In situ Regeneration of Bioactive Coatings using evolved Staphylococcus Aureus Sortase A
H. O. Ham , Z. Qu, E. Chaikof
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

Macromolecular Drug Delivery

731. Multifunctional SPIO Labeled Calcium Phosphate Microparticles for Localized Therapeutic Protein Delivery
A. E. B. Clements ¹ , C. S. Chamberlain¹, E. Aktas², R. Vanderby, Jr.¹, W. L. Murphy ^1
1 University of Wisconsin-Madison, Madison, WI, ²Ankara Oncology Research and Training Hospital, Ankara, Turkey

732. Polymersomes: Towards Treatment of Neurodegenerative Disorders through Enzyme Replacement Therapy
J. Larsen ¹ , E. Pearce¹, D. Martin¹, M. Byrne ^2
1 Auburn University, Auburn, AL, ²Rowan University, Auburn University, Glassboro, NJ

Materials and Matrices for Osteochondral Tissue Engineering

733. Cell-laden Nanofibrous Membrane Design for Osteochondral Repair
J. Park, M.J. Kim, G.Z. Jin, H.W. Kim
Dankook University, Cheonan, Republic of Korea

734. Analysis of Alkaline Phosphatase Expression and Tissue Mineralization in a Woven Tissue Engineering Test System
J. Gilmore ¹ , F. Yin¹, K. J. L. Burg ^2
1 Clemson University, Clemson, SC, ²Kansas State University, Manhattan, KS

735. Fabrication of a TGF-β3 Encapsulated PLCL Scaffold by Supercritical CO2-HFIP Co-Solvent System
S. H. Kim, S. H. Kim, Y. Jung
Korea Institute of Science and Technology, Seoul, Republic of Korea

736. Collagen-Alginate-Hyaluronan Composite Hydrogels for Effective Culture and Maintenance of Chondrocytes
C. Mahapatra, J. G. Zhen, H.-W. Kim 
Dankook University, Cheonan, Republic of Korea

Mechanical Characterization of Biomaterials

737. Finite Element Analysis of a Single Barbed Suture Using Beam Theory
M. Jeffries ¹ , J. S. Strenkowski¹, J. Cole¹, G. L. Ruff², M. W. King ^1
1 North Carolina State University, Raleigh, NC, ²Private clinic, Chapel Hill, NC

738. Molecular Modulation of Long Lasting Absorbable Polymers for Compliance and Selective Degradation
J. A. Lilley , K. D. Gray, M. S. Taylor
Poly-Med, Inc, Anderson, SC

739. The Stress-Relaxation Behaviors of Collagen-Depleted Heart Valve Tissues
S. Huang, H.-Y. S. Huang
North Carolina State University, Raleigh, NC

740. Biomechanical and Biochemical Study of Muscle-Tendon Junctions and Tendon-Bone Insertions
B. Danley , X. Wu, M. Pankow, K. Peters, H.-Y. S. Huang
North Carolina State University, Raleigh, NC

741. In vivo Evaluation of Cervical Stiffness Evolution during Induced Ripening Using Shear Waves Elastography: Insight from an Animal Model
L. Peralta Pereira¹, E. Mourier², C. Richard², M. Tanter³, G. Rus⁴, P. Chavatte-Palmer², M. Muller ^5
1 University of Granada, Granada, Spain, ²INRA UMR 1198 Biologie du Développement et Reproduction, Jouy en Josas, France, ³Institut Langevin, Paris, France, ⁴University of Granada, Granada, Spain, ⁵NC State University, Raleigh, NC

742. Multiple Length-Scale Spherical Indentation of PEG and Alginate-Based Hydrogels
J. M. Shapiro ¹ , B. G. Bush², F. W. DelRio², R. F. Cook², C. A. Stratakis¹, M. L. Oyen ^3
1 National Institutes of Health, Bethesda, MD, ²National Institute of Standards and Technology, Gaithersburg, MD, ³University of Cambridge, Cambridge, United Kingdom

743. Tg and Fragility Determination of Glass-Forming Sugars using a Dynamic Mechanical Analyzer
L. Weng , G. D. Elliott
University of North Carolina at Charlotte, Charlotte, NC

Modulating the Neural Microenvironment

744. In vitro Study of Astrocyte and Macrophage Response to Silicon Surface Modified with Cationic Microgels
E. Morin , S. Tang, K. Rogers, W. He
University of Tennessee, Knoxville, Knoxville, TN

745. Magnesium Ferrite for Neural Applications
Z. S. Thompson
North Carolina A&T State University, Greensboro, NC

746. The Chronic FBR and Recording Performance in Aged Rat Cortex using High Density Silicon Recording Arrays
M. B. Christensen , N. F. Nolta, P. A. Tresco
University of Utah, Salt Lake City, UT

747. Markers of BBB Leakiness Correlate with Single Unit Recording Performance in High Density Penetrating Electrode Arrays Implanted Chronically in Rat Motor Cortex
N. F. Nolta , M. B. Christensen, P. A. Tresco
University of Utah, Salt Lake City, UT

748. Controlling the Local Environment to Improve Schwann Cell Response
J. Stukel , W. Zhou, R. Willits
The University of Akron, Akron, OH

749. Transcranial Direct Current Stimulation (tDCS) Enhances Recovery From Motor Deficits Following Neonatal HIE Stroke
C. L. Anderson
University of Florida, Gainesville, FL

Molecular Mechanisms Governing Protein-Surface and Cell-Surface Interactions

750. The Role of Molecular Interaction Forces in Protein Adsorption Process on Materials Surfaces
S. Sakata , Y. Inoue, K. Ishihara
The University of Tokyo, Tokyo, Japan

751. Crosstalk between Integrin-β1 and BMPR1A Mediate Matrix Regulated MSC Osteogenesis
R. Guo ¹ , S. Lu¹, J. M. Page², J. A. Sterling³, S. A. Guelcher ^1
1 Vanderbilt University, Nashville, TN, ²Research and Development Engineer at MicroPort Orthopedics Inc, Arlington, TN, ³Department of Veterans Affairs: Tennessee Valley Healthcare System and Department of Medicine, Nashville, TN

752. The Effect of Network Properties on the Antifouling Properties of Amphiphilic Crosslinked Networks
L. Villada , C. Kizilkaya, A. B. Brennan
University of Florida, Gainesville, FL

Multifunctional Nanomaterials for Engineering Complex Tissues and Drug Delivery

753. Targeted Drug Delivery via Magnetic Nanoparticles: Novel Treatment for Canine Osteosarcoma
A. Kovach , T. Szasz, Z. Nelson, M. Cavalcanti, J. Gambino, L. Williams, J. Liao, R. Prabhu
Mississippi State University, Mississippi State, MS

754. High Surface Area Patterned Hydrogels for Drug Delivery or Tissue Engineering Applications
M. Caldorera-Moore
Louisiana Tech University, Ruston, LA

755. Polymeric Micelle as a Nucleic Acid Carrier for Axonal Regeneration in CNS
S. Gwak , B. Green, C. Macks, K. Webb, J. S. Lee
Clemson University, Clemson, SC

756. Polymeric Micelle as a Drug and Gene Delivery Carrier for Brain Tumor
B. Green , S. Gwak, G. Temples, J. S. Lee
Clemson University, Greenville, SC

757. Tumor-Targeting Upconversion–Nanoparticle-Based Unimolecular Micelles for Simultaneous Chemotherapy, Photodynamic Therapy, and Fluorescence Imaging
G. Chen, L. Wang, S. Gong
University of Wisconsin-Madison, Madison, WI

Multiscale Biomaterial Design

758. Encapsulating Hydrogels with Multi-Scale Porosity for Islet Transplantation to Treat Type 1 Diabetes
P. Rios , X. Zhang, X. Luo, L. Shea
Northwestern University, Chicago, IL

759. Effects of processing on Glycoprene® 6829 Glycolide/Caprolactone/Trimethylene Carbonate polyaxial random copolymer: A preliminary report
C. DiRuscio , G. Hilas, S. McCullen, M. S. Taylor
Poly-Med, Inc., Anderson, SC

760. Mechanical Properties of Polypropylene-ePTFE Surgical Mesh Explanted After in vivo Function
E. Casey
Clemson University, Central, WV

761. Mechanically Tunable Hyaluronan-Based Hydrogels for Dental Pulp Stem Cell Growth
S. Ananthula , K. B. Compton, D. R. Janagam, T. L. Lowe
University of Tennessee Health Sciences Center, Memphis, TN

Multi-Scale Materials Design for Abiotic-Biotic Interfaces

762. Anisotropic Supported Lipid Bilayers for Spatially Dynamic Surface Protein Presentation
R. A. Meyer , M. P. Mathew, J. C. Sunshine, R. B. Shmueli, Q. Ren, K. J. Yarema, J. J. Green
Johns Hopkins University, Baltimore, MD

Nanobiomaterial and Drug Delivery Strategies for Dental/Craniomaxillofacial Repair/Regeneration

763. Biosynthetic Materials Facilitate Effective Neurosurgical Closure
M. MacEwan ¹ , T. Kovacs², W. Ray ^1
1 Washington University School of Medicine, Saint Louis, MO, ²Acera Surgical, Inc., Saint Louis, MO

764. Random Acrylate Copolymer Surface Grafting to Poly(dimethyl siloxane) Elastomer Surfaces for Improved Anti-Biofouling
C. Kuliasha ¹ , L. Villada¹, J. Royal¹, J. Finlay², M. Callow³, J. Callow³, T. Clare², A. Brennan ^1
1 University of Florida, Gainesville, FL, ²University of Newcastle, Newcastle upon Tyne, United Kingdom, ³University of Birmingham, Birmingham, United Kingdom

765. Evaluation of a Ciprofloxacin and Metronidazole Encapsulated Biomimetic Nanomatrix Gel on Enterococcus faecalis and Treponema denticola
S. Kaushik¹, T. Walker¹, J. Park², J. Scoffield¹, A. Andukuri¹, G. Alexander ¹, B. Brott¹, P. Eleazer¹, H. Wu¹, N. Childers¹, H. Jun¹, K. Cheon ^1
1 University of Alabama at Birmingham, Birmingham, AL, ²Kyung Hee University, Seoul, Republic of Korea

766. Controlled Release of Simvastatin from Anodized Ti Granules for Improving Its Antibacterial Effects
Z. Gorgin Karaji¹, B. Houshmand², M. Jamadi Khiabani¹, S. S. Shafiei ^1
1 National Institute of Genetic Engineering and Biotechnology, Tehran, Iran, ²Shahid Beheshti University of Medical Sciences, Tehran, Iran

767. Antimicrobial Effect of Calcium Phosphate Spheres decorated with Ag nanodots on Periodontal Pathogens
T. B. Martin ¹ , D. A. V. Pulgarin¹, J. P. Babu², M. Shahbuddin¹, J. A. Jennings¹, J. D. Bumgardner ¹, S. R. Mishra ^1
1 University of Memphis, Memphis, TN, ²School of Dentistry, UTHCS-Memphis, Memphis, TN

Nanomaterials

768. Surfactant Functionalization Induces Robust, Differential Adhesion of Tumor Cells and Blood Cells to Charged Nanotube-Coated Biomaterials Under Flow
M. J. Mitchell ¹ , C. Castellanos², M. King ^2
1 MIT, Cambridge, MA, ²Cornell University, Ithaca, NY

769. Effect of Red Selenium Nanoparticles on Head and Neck Squamous Cell Carcinoma
C. E. Hassan
Northeastern University, North Easton, MA

770. Synthesis of Core/Shell Nanorod of Bismuth Doped Hydroxyapatite with Improved Antimicrobial Characteristics: A Facile Approach
M Selvakumar ¹ , S. K. Jaganathan², S. Chattopadhyay¹, G. B. Nando ^1
1 Indian Institute of Technology Kharagpur, Kharagpur, India, ²Universiti Teknologi Malaysia, Malaysia, Malaysia

771. Control of Clustered Iron Oxide Interparticle Spacing and Their Magnetic Properties
D. Wang , B. Lin, H. Ai
National Engineering Research Center for Biomaterials, Sichuan University, China, Chengdu, China

772. Synthesis and Characterization of CREKA-conjugated Iron Oxide Nanoparticles for Hyperthermia Applications
A. K. Hauser , K. W. Anderson, Z. Hilt
University of Kentucky, Lexington, KY

773. Functional Clay Nanotube-Enzyme Biocomposites
J. Tully , R. Yendluri, Y. Lvov
Louisiana Tech University, Ruston, LA

774. Long Term Delivery of Nerve Growth Factor by Nano/Microparticles for Enhancing Peripheral Nerve Regeneration
A. D. Sharma , M. Uz, D. S. Sakaguchi, S. K. Mallapragada
Iowa State University, Ames, IA

775. Target-Specific Stimuli-Responsive Protoporphyrin IX Polysilsesquioxane Nanoparticles to Improve Photodynamic Therapy for Cancer Treatment
J. L. Vivero-Escoto , Z. Lyles, D. L. Vega
University of North Carolina at Charlotte, Charlotte, NC

776. Functionalized Polymersomes for Trapping the Ebola Virus
C. Li , B. M. Geilich, T. J. Webster
Northeastern University, Boston, MA

777. Multifunctional Mesoporous Silica Nanoparticles for the Delivery of Cisplatin and Gemcitabine to Treat Cancer
E. Fink , A. Hashemi, J. Pan, M. Alvarez-Berrios, J. Vivero-Escoto
University of North Carolina at Charlotte, Charlotte, NC

778. Reducing Bacterial Adhesion on Surface Modified Titanium
H. Yazici , T. J. Webster
Northeastern University, Boston, MA\

779. Shape and Surface Effects on the Cytotoxicity of Gold Nanospheres and Gold Nanostars
P. M. Favi ¹ , M. Gao¹, L. J. S. Arango², S. P. O. Alvarez², M. M. Valencia², T. J. Webster ^1
1 Northeastern University, Boston, MA, ²University of Antioquia, Medellín, Colombia

780. EDTA Loaded BSA Nanoparticles for Targeted Therapy to Reverse Vascular Calcification in Chronic Kidney Disease Animal Model
S. R. Karamched , N. Nosoudi, N. Vyavahare
Clemson University, Clemson, SC

781. Gellan-Gum Coated Gold Nanorods as Intracellular Drug Release System for Regenerative Medicine
S. Vial ¹ , S. Vieira¹, M. Carvalho¹, R. L. Reis¹, P. L. Granja², J. M. Oliveira ^1
1 3B´s Research Group, Taipas, Portugal, ²Instituto de Engenharia Biomedica, Porto, Portugal

Nanotherapeutics for Cardiovascular Applications

782. Keratose as a Novel Drug Carrier for Drug Coated Balloons
E. Turner ¹ , S. Tomblyn², L. Burnett², S. K. Yazdani ^1
1 University of South Alabama, Mobile, AL, ²KeraNetics, Winston-Salem, NC

783. Multi-Functional Nanoparticle Development for Glycocalyx Heparan Sulfate Regeneration on Cultured Endothelial Cells
M. Cheng , H. Homayoni, R. Kumar, S. Sridhar, T. Webster, E. Ebong
Northeastern University, Boston, MA

784. Multifunctional Magnetic Nanoparticles to Restore Elastic Matrix Homeostasis in Abdominal Aortic Aneurysms
B. Sivaraman , G. Swaminathan, L. Moore, M. Zborowski, A. Ramamurthi
Cleveland Clinic, Cleveland, OH

Next Generation Biomaterial and Drug Delivery Technologies for Wound Healing

785. Microfluidic-Based Generation of Protease-Degradable PEG-MAL Microgels for Protein Delivery
C. Gonzalez Garcia ^1,2 , D. Headen¹, M. Salmeron-Sanchez², A. J. Garcia ^1
1 Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, Atlanta, GA, ²Biomedical Engineering Research Division, University of Glasgow, Glasgow, UK, Glasgow, United Kingdom

786. Nitric Oxide-Releasing Electrospun Polyurethane Wound Dressings
B. V. Worley , R. J. Soto, M. H. Schoenfisch
University of North Carolina-Chapel Hill, Chapel Hill, NC

787. Tunable Polyester Matrices Based On Sebacic Acid Using Crosslinking As A Strategy In Combinatorial Approach
Y. Chandorkar , G. Madras, B. Basu
Indian Institute of Science, Bangalore, India

788. High Moisture Vapor Transmission Rate and High Fluid Absorption Films for Wound Dressings
L. Miinea , P. Basone, A. Camardo, J. Baxter, E. Rohr, N. Marchant
Lubrizol Advanced Materials, Inc., Cleveland, OH

789. Growth Factor Release from poly(ethylene glycol) diacrylate Hydrogels as a Treatment for Chronic Wound Healing
P. Krzyszczyk , R. Olabisi
Rutgers University, Piscataway, NJ

790. Effect of Polymer Architecture on Physical and Mechanical Properties of High Glycolide Content Polymers
S. McCullen , C. Culbreath, J. E. Dixon, J. Corbett, M. S. Tayor
Poly-Med, Inc., Anderson, SC

791. Biofunctionalized Hydrogels for Intestinal Epithelial Stem Cell Delivery
R. Cruz-Acuna ¹ , A. E. Farkas², A. Nusrat², A. J. García ^1
1 Georgia Institute of Technology, Atlanta, GA, ²Emory University School of Medicine, Atlanta, GA

792. Bioresorbable ureteral stent translation for in vivo model
A. A. A. Barros ¹ , C. Oliveira², E. Lima², R. A. C. Duarte³, R. L. Reis ^3
1 3B's Research Group of University of Minho, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ³3B's Research Group, Guimarães, Portugal

793. Delivery of Doxycycline from PLGA-Coated Hernia Meshes
T. A. Q. Phan , D. A. Puleo
University of Kentucky, Lexington, KY

794. Self-Assembling MMP-2 Cleavable Hydrogel Drug Delivery Systems; Neural Tissue Biocompatibility and Response
K. M. C. Koss ¹ , M. Churchward², K. Todd³, L. D. Unsworth ^2
1 University of Alberta National Institute for Nanotechnology, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³ Psychiatry, Edmonton, AB, Canada

795. Fabrication and Characterization of Hybrid Polymeric Scaffolds
A. H. Najarzadeh , D. A. Puleo, IV
University of Kentucky, Lexington, KY

796. Heparin-eluting Vascular Suture for Preventing Thrombosis and Stenosis
M. DiBalsi ¹ , S. Bae¹, J. S. Lee², G. Korneva¹, K. Kornev ^1
1 Clemson University, Clemson, SC, ²Clemson University, Greenville, SC

797. Highly Elastic Nanofibrous Scaffolds for Skin Tissue Engineering Applications
M. Mohiti-Asli ¹ , C. Molina¹, K. Rietzler², B. Pourdeyhimi², E. G. Loboa ^1
1 University of North Carolina Chapel Hill and North Carolina State University, Raleigh, NC, ²The Nonwovens Institute, North Carolina State University, Raleigh, NC

798. In Vitro and In Vivo Degradation and Biocompatibility Evaluation of Chitosan Sponges and Paste
C. S. Rhodes , M. Whitaker, A. C. Parker, H. Doty, J. A. Jennings, W. O. Haggard
The University of Memphis, Memphis, TN

799. Arabinoxylan Sponges for Wound Healing Applications
D. C. Aduba, Jr. , A. Yeudall, H. Yang
Virginia Commonwealth University, Richmond, VA

Ophthalmic Biomaterials

800. Purification of an Acrylic IOL Dye Additive by a Solvent Washing Process – Effect of Precipitation Temperature
D. Urbaniak , M. D. Lowery
Abbott Medical Optics, Santa Ana, CA

Ophthalmic Biomaterials

801. A Suspension of Porcine Cartilage Extra-Cellular Matrix Exerts Anti-Angiogenic Effect in a Rabbit Corneal Model
H.-W. Yun ¹ , S. Y. Kim¹, B. R. Song¹, T.-i. Kim², B. H. Choi³, Y. J. Kim¹, S. R. Park³, S.-H. Park ⁴, B.-H. Min ^1
1 Ajou University, Suwon, Republic of Korea, ²Yonsei University, Seoul, Republic of Korea, ³Inha University, Incheon, Republic of Korea, ⁴Jungwon University, Goesan, Republic of Korea

Orthopaedic Biomaterials

802. Collagen Self-Assembly on Orthopedic Magnesium Biomaterials Surface and Subsequent Bone Cell Attachment
N. ZHAO , J. Ma, D. Zhu
North Carolina A&T State University, Greensboro, NC

803. Effect of Poisson’s Ratio on the Intrinsic Mechanical Properties of Poly (Vinyl Alcohol) Hydrogels: Preliminary Results
M. A. Vaughn ¹ , K. J. L. Burg², J. T. Corbett ^3
1 Poly-Med, Inc./Clemson University, Anderson, SC, ²Clemson University / Kansas State University, Manhattan, KS, ³Poly-Med, Inc., Anderson, SC

804. Structural Analysis of Gallium Based Glass Polyalkenoate Cements by Infrared Spectroscopy
A. M.F. Alhalawani , D. Curran, M. Towler
Ryerson University, Toronto, ON, Canada

805. Osteogenic and Antimicrobial Properties of Chitosan Treated Titanium Surface in a Co-Culture System of Peri-Operative Infection Model: an in vitro Study
N. Ghimire ¹ , Y. Sun², Y. Deng ^1
1 The University of South Dakota, Sioux Falls, SD, ²The University of Massachusetts, Lowell, MA

806. Microwave Processing of Amorphous Magnesium-Calcium Phosphate
E. Babaie , Y. Ren, S. B. Bhaduri
University of Toledo, Toledo, OH

807. Modularly assembled hyaluronic acid hydrogels with tunable stimuli responsiveness
W. M. Gramlich
University of Maine, Orono, ME

808. Patterning Bone Formation Using Proteins Derived from Seashell and Bone
K. A. White , R. M. Olabisi
Rutgers, The State University of New Jersey, Piscataway, NJ

809. DC Stimulation for Spinal Fusion with a Piezoelectric Composite Material Interbody Implant: An Ovine Pilot Study
L. Friis ¹ , N. Galvis¹, P. Arnold ^2
1 University of Kansas, Lawrence, KS, ²University of Kansas Medical Center, Kansas City, KS

810. Semi-Resorbable Composite PMMA-Brushite Bone Cement for Spinal Augmentation
S. Aghyarian , E. Bentley, D. Rodrigues
The University of Texas at Dallas, Richardson, TX

811. Quantitative Assessment of Taper Damage and Head-Neck Moment Arm on Retrieved Total Hip Replacements with Modular Bore-Cone Taper Junctions
C. M. Stamer , R. Taylor, P. Panigrahi, M. Harman
Clemson University, Clemson, SC

812. Role of Citric Acid on Apatite Nucleation and Osteogenic Differentiation of Human Mesenchymal Stem Cells on Aligned Nanofibers
D. Barati , S. R. Pajoum Shariati, S. Moeinzadeh, E. Jabbari
University of South Carolina, Columbia, SC

813. Effects of Heat Treatment on the Tensile Strength and Transition Temperature of Processed Collagen Devices
M. Al-Rajhi , M. Diaz, A. Woodruff, G. Pomrink
NovaBone Products, Alachua, FL

814. Osteoblastic Stimulation through Gene Silencing Approach using Mesoporous Nanocarriers
J. Kim , M. Kang, T. Kim, S. Seo, H. Kim
Dankook University, Cheonan, Republic of Korea

Proteins and Cells at Interfaces

815. Extension, Locomotion, and Proliferation of Osteoblast-like Cells on Metals
P. Chen , Y. Tsutsumi, M. Ashida, H. Doi, T. Hanawa
Tokyo Medical and Dental University, Tokyo, Japan

816. Cellular and Gene Expression Responses in Osteoblast-like Cells to Metals
P. Chen , Y. Tsutsumi, M. Ashida, H. Doi, T. Hanawa
Tokyo Medical and Dental University, Tokyo, Japan

817. Bacterial Surface Display for Discovery and Study of Material Specific Peptides
B. L. Adams , M. Hurley, D. A. Sarkes, D. Stratis-Cullum
US Army Research Laboratory, Adelphi, MD

818. Nanotubular Composites Decorated on Titanium to Regulate Cell Responses
H.-W. Kim, C. Mahapatra, J.-J. Kim, T.-H. Kim, K. D. Patel
Dankook University, Cheonan, South Korea

Recent Advances in Surface Modification of Biomaterials

819. Methods and Reagents for Islet Surface Modification
R. R. Kane ¹ , C. Chang¹, J. M. Horton¹, M. A. Kanak¹, B. Naziruddin ^2
1 Baylor University, Waco, TX, ²Baylor University Baylor University Medical Center, Dallas, TX

820. Photoinduced and Self-Initiated Grafting of 2-Methacryloyloxyethyl Phosphorylcholine to Poly(ether-ether-ketone): Effects of Inorganic Salt for Shortening the Graft Polymerization Time
K. Ishihara , T. Shiojima, M. Kyomoto
The University of Tokyo, Tokyo, Japan

821. Surface Modification of CoCr alloy Using Phosphoric and Phosphonoacetic Acids: Protein and Platelet Interactions
E. Thiruppathi¹, M. Larson², G. Mani ^1
1 University of South Dakota, Sioux Falls, SD, ²Augustana College, Sioux Falls, SD

822. Surface Characterization and Corrosion Behavior of Silanized Magnesium Coated With Graphene for Biomedical Application
M. P. Neupane , Y. K. Kim, J. H. Ji, I. S. Park, T. S. Bae, M. H. Lee
Chonbuk National University, Jeonju, Republic of Korea

823. Biological Investigation of PEG-Containing Siloxane Materials by Metal-Free Click-Chemistry
F. Lasowski , T. Rambarran, M. A. Brook, H. Sheardown
McMaster University, Hamilton, ON, Canada

824. Hydroxyapatite Coating on PEEK: Material Processing, Analysis and Biocompatibility Study
J. W. Durham, III , A. Rabiei
North Carolina State University, Raleigh, NC

825. Development of Nanoscale Hydrogel Coatings in High Speed Cell Sorting
J. L. Lilly , B. J. Berron
University of Kentucky, Lexington, KY

826. Light-sensitive Fluoropolymer Coated Surface for Control of Cell Adhesion Behavior
M. Nakayama ¹ , T. Kanno², A. Kikuchi², T. Okano ^1
1 Tokyo Women's Medical University, Tokyo, Japan, ²Tokyo University of Science, Tokyo, Japan

827. Biological tethering of N-Cadherin to Substrates Promotes Cell-Cell Adhesion
J. C. M. Vega, M. K. Lee, D. E. Leckband, H. Kong
University of Illinois at Urbana-Champaign, Urbana, IL

828. Effect of Micropattern Dimensions on Adhesion, and Nuclear Shape of Osteosarcoma Cells
M. Ermis ¹ , D. Akkaynak², P. Chen³, U. Demirci³, V. Hasirci ^1
1 METU Center of Excellence in Biomaterials and Tissue Engineering (BIOMATEN), Ankara, Turkey, ²Massachusetts Institute of Technology, Cambridge, MA, ³Stanford University School of Medicine, Palo Alto, CA, ³Stanford University School of Medicine, Palo Alto, CA

Small Molecule Drug Delivery

829. WITHDRAWN

830. Test Methodology of Characterizing the Behavior of Injectable Hydrogels: An In Vitro Model
J. L. Isaacs ¹ , V. Binetti², K. Kita³, A. Lowman⁴, M. Marcolongo ^2
1 Widener University, Chester, PA, ²Drexel University, Philadelphia, PA, ³DePuy Synthes, West Chester, PA, ⁴Rowan University, Glassboro, NJ

831. In Vivo Effects of Levonorgestrel Containing In Situ Gelling Drug Delivery Systems on Rat Pregnancy
S. Ananthula , k. Chaudhry, D. R. Janagam, J. R. Johnson, T. Mandrell, T. L. Lowe
University of Tennessee Health Sciences Center, Memphis, TN

832. Conjugation of Bicyclol-Polymer Conjugates for Protecting Liver from Injury
L. Wang ¹ , T. Lu ^2
1 University of Tennessee Health Science Center, Memphis, TN, ²University of Tennessee, Memphis, TN

Stem Cell and Biomaterial Interactions

833. Assessing the Osteogenic Differentiation of Human Mesenchymal Stem Cells Co-Cultured with Human Vein Endothelial Cells on a Peptide Amphiphile Nanomatrix
L. Deng, D. Patel, J. B. Vines, A. Javed, S. R. Gilbert, H. Jun
University of Alabama at Birmingham, Birmingham, AL, Birmingham, AL

834. Hydrogel Microencapsulation Mimics Whole Body Response to Low Magnitude High Frequency Vibration
S. Mehta , R. M. R. Olabisi
Rutgers University, Piscataway, NJ

835. Gold Nanoparticles Actuates Human Mesenchymal Stem Cell Differentiation under Electric Field Stimulation
G. Thrivikraman , G. Madras, B. Basu
Indian Institute of Science, Bangalore -560012, Bangalore, India

836. Dynamic Extracellular Control of Mesenchymal Stem Cell Angiogenic Potential
A. Abdeen , J. Lee, K. Kilian
University of Illinois at Urbana Champaign, Urbana, IL

837. Matrix Rigidity-Modulated Cardiovascular Organoid Formation from Embryoid Bodies
A. Shkumatov, K. Baek, H. Kong
UIUC, Urbana, IL

838. Susceptibility of Macroporous PHEMA Hydrogels for Growth of Mouse Embryonic Stem Cells
O. Janouskova , M. Přádný, M. Dušková-Smrčková, K. Dušek, M. Šlouf, J. Michálek
Institute of Macromolecular Chemistry v.v.i., AS CR, Prague 6, Czech Republic

839. Magnetic Field Triggered Osteogenic Differentiation of Human Mesenchymal Stem Cells on Ferromagnetic Substrates
S. K. Boda , G. Thrivikraman, B. Basu
Indian Institute of Science, Bangalore, India

Surface Characterization and Modification

840. Multi-Scale Surface Modification on Ti-6Al-4V alloy by SPE process
B. Moon ¹ , T. Jang², S. W. Kim¹, J. Song¹, H. Kim ^1
1 Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea, ²Seoul National University, Seoul, Republic of Korea

841. Surface Response Model Characterizing and Predicting Selenium Nanoparticle Coatings on Medical Devices
M. Stolzoff
Northeastern University, Boston, MA

842. WITHDRAWN

843. Evaluation of Protein Hydration by Vapor Sorption Methods
D. J. Burnett ¹ , M. Naderi², A. Kondor², M. Acharya ^2
1 Surface Measurement Systems, Allentown, PA, ²Surface Measurement Systems, Alperton, United Kingdom

844. Mucoadhesive Surface Modification of PHEMA hydrogel for Ophthalmic Drug Delivery Application
L. Liu , H. D. Sheardown
McMaster University, Canada, Hamilton, ON, Canada

845. A t-PA/gold Nanoparticle Conjugate Based on Bio-affinity Ligation
Z. Tang , D. Li
Soochow University, Suzhou, China

846. Surface Characterization of Nanoparticles for Biomedical Applications
Y. Wang, A. Rafati, D. G. Castner
University of Washington, Seattle, WA

847. Surface Modification using Polydopamine to Adhere a Novel Anticoagulant Antithrombin-Heparin Complex to the Surface of PDMS Oxygenators used as a Lung Assist Device for Neonates
D. Sandejas ¹ , J. Brash¹, C. Fusch², A. Chan¹, N. Rochow¹, G. Fusch¹, L. Berry³, H. Atkinson⁴, J. Leung¹, R. Cornelius¹, H. Matharoo¹, R. Selvaganapathy ^1
1 McMaster University, Hamilton, ON, Canada, ²McMaster University, Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada, ³Thrombosis and Atherosclerosis Research Institute, Pediatrics, Hamilton, ON, Canada, ⁴Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada

Targeted and Target-Activated Drug Delivery

848. Selective Inhibition of MG-63 Osteosarcoma Cell Proliferation Induced By Curcumin-Loaded Self-assembled Arginine-Rich-RGD Nanospheres
R. Chang , L. Sun, T. J. Webster
Northeastern University, Boston, MA

849. Synthesis and In Vitro Assessment of Folate-targeted Polyamidoamine Dendrimer Gene Vector
L. Xu , A. Yeudall, H. Yang
Virginia Commonwealth University, Richmond, VA

850. Folate-targeted Polyamidoamine Dendrimer for Head and Neck Cancer Gene Therapy
L. Xu , A. Yeudall, H. Yang
Virginia Commonwealth University, Richmond, VA

Technology Development/ New Biomaterials for Immune Engineering

851. Micro and Nano-patterned Surface Topographies for Control of Macrophage Form and Function
T. U. Luu ¹ , S. C. Gott², M. P. Rao², W. F. Liu ^1
1 University of California, Irvine, Irvine, CA, ²University of California, Riverside, Riverside, CA

852. Self-assembled Glycopeptide Nanofibers as Synthetic Glycoprotein Mimetics to Modulate Lectin Bioactivity
A. Restuccia, Jr. , G. A. Hudalla
The University of Florida, Gainesville, FL

Theranostic Nanomaterials for Image-Guided Treatments

853. Fibrin Glue Does Not Increase Drug Retention in the Spine
M. B. Giers ¹ , K. Cronk², Q. Lui¹, G. Ide¹, M. Preul³, N. Theodore ^4
1 St. Joseph's Hospital and Medical Center, Phoenix, AZ, ²New England Neurological Associates, P.C. St. Joseph’s Hospital and Medical Center, Lawrence, MA, ³Barrow Neurological Institute St. Joseph's Hospital and Medical Center, Phoenix, AZ, ⁴Barrow Neurological Institute, Phoenix, AZ

854. Optimization of the Morphology of Multifunctional Mesoporous Silica Nanoparticles to Increase Therapeutic and Diagnostic Effects in Breast Cancer
A. L. Nelson
UC Denver Anschutz Medical Campus, Denver, CO

855. Polymeric Nanoparticle-Based Enzymatically Activatable Near-Infrared Nanoprobes for Optical Detection of Cancer
T. Ozel ¹ , S. White², E. Nguyen², A. Moy², B. Choi², T. Betancourt ^1
1 Texas State University, San Marcos, TX, ²University of California-Irvine, Irvine, CA

Tissue Engineering

856. MC3T3 Cells Co-Cultured with Macrophages Demonstrate Enhanced Osteogenic Differentiation
F. Loi , R. Zhang, K. Barcay, H. Rogan, T. Lin, J. Pajarinen, C. Fan, T. Sato, J. Raphel, Z. Yao, S. Goodman
Stanford University, Stanford, CA

857. Multiple Layer Nerve Guide Using Carbon Nanotubes for Peripheral Nerve Regeneration
X. Lu ¹ , O. Yildiz², P. Bradford ^2
1 Clemson University, Clemson, SC, ²North Carolina State University, Raleigh, NC

858. New Bioactive Glass Fibers for Soft Tissue Regeneration
M. T. Souza ¹ , O. Peitl¹, M. B. Puzzi², E. D. Zanotto ^1
1 Federal University of Sao Carlos, Sao Carlos, Brazil, ²State University of Campinas, Campinas, Brazil

859. The Analysis of Residual Enzyme in the Cartilage Tissue after Partial Digestion
P. Lee ¹ , C. Chen¹, A. McNally², K. Sly², C. Chapman², S. Lin ^2
1 Exactech Taiwan, Hsinchu County, Taiwan, ²Exactech Inc., Gainesville, FL

860. Micro-Computed Tomography Technique to Study a Porouse Biphasic Scaffold
A. J. McNally , C. Chapman, K. Sly, L. Krengel, S. Lin
Exactech, Inc., Gainesville, FL

861. Microtopographical Effects on Differentiation of Embryonic Stem Cells into Cardiomyocytes
N. R. Patel , A. Whitehead, C. Tran, J. Newman, M. Caldorera-Moore
Louisiana Tech University, Ruston, LA

862. Protein Based Biocomposite Cryogels as Tissue Engineering Scaffolds
K. Kutuk
Yıldız Technical University, Istanbul, Turkey

863. New blood compatible polymers for the maintenance of hepatocyte functions to develop bioartificial liver.
T. Hoshiba , T. Otaki, M. Tanaka
Yamagata University, Yonezawa, Japan

864. Effects of the Orientation of Anti-BMP2 Monoclonal Antibody Immobilized on Scaffold in Antibody Mediated Osseous Regeneration
H. Zadeh
University of Southern California, Los Angeles, CA

865. Hybrid Nanofibers Designed to Deliver Oxygen Favorable for Cell Survival and Osteogenesis
H. Lee ¹ , J. Kim², S. Seo², H. Kim ^2
1 Institute of Tissue Regeneration Engineering (ITREN), Cheonan, Republic of Korea, ²Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea

866. Collagen Crosslinking Agent Injections to Reduce Soft Palate Vibrations in Equine Snoring
S. Hunt ¹ , J. Kuo², T. Hedman ^1
1 University of Kentucky, Lexington, KY, ²University of Kentucky, Silver Spring, MD

867. Strategic Design of Electrospun Fiber Scaffolds to Deliver Multiple Growth Factors for Bone Regeneration
M. S. Kang , J. J. Kim, H.-Y. Lee, J.-H. Kim, H.-W. Kim
Dankook University, Cheonan, Republic of Korea

868. WITHDRAWN

869. Resveratrol Nanoparticle-incorporated Scaffolds to Modulate Inflammation and Promote Osteogenesis
K. E. Rutledge , E. Jabbarzadeh
University of South Carolina, Columbia, SC

870. Biomimetic Polymer Conduit for Nerve Guidance Following Peripheral Nerve Injury
D. J. Lee
University of Colorado, Anschutz Medical Campus, Superior, CO

871. Bioengineering Polycaprolactone Scaffolds for Growing Human Trabecular Meshwork Cells
J. R. Halman ¹ , K. Y. Torrejon², L. A. Beardslee², M. Bergkvist², S. T. Sharfstein², Y. Xie ^2
1 SUNY Polytechnic Institute, Scarsdale, NY, ²SUNY Polytechnic Institute, Albany, NY

Vaccine Delivery Vehicles

872. Hybrid Calcium Carbonate-Peptide Nanofiber Microparticles for Mucosal Antigen Delivery
J. Snook ¹ , C. Chesson¹, A. Zloza², J. Rudra ^1
1 University of Texas Medical Branch, Galveston, TX, ²Rush University Medical Center, Chicago, IL

873. Adjuvant Conjugated Microparticles for Vaccine Delivery: A Robust Method to Promote Immune Response
K. Brink , M. V. Pishko
Texas A&M University, College Station, TX

Vascular and Blood Cells Responses to Novel Cardiovascular Biomaterials

874. Effects of Magnesium on Endothelial Barrier Functions
N. Zhao , J. Ma, D. Zhu
North Carolina A&T State University, Greensboro, NC

875. Prohealing Multifunctional Endothelium Nanomatrix Coated Stents
G. Alexander ¹ , A. Andukuri¹, Y. Sohn², Y. Yoon², P. Anderson¹, J. Kim¹, B. Brott¹, H. Jun ^1
1 University of Alabama at Birmingham, Birmingham, AL, ²Emory University, Atlanta, GA

876. Inhibition of Smooth Muscle Cell Growth by Paclitaxel Releasing Polyethylene Oxide films for Drug-Coated Balloons
J. Anderson , G. Mani
The University of South Dakota, Sioux Falls, SD

877. How Adsorbed Fibrinogen Conformation Affects Platelet Adhesion
B. J. Casey ¹ , L. Zhang², K. Vorvolakos¹, D. Galanakis², M. H. Rafailovich ^2
1 U.S. Food and Drug Administration, Silver Spring, MD, ²Stony Brook University, Stony Brook, NY

878. An In Vitro Study on Early Inflammatory Response to Four Magnesium-Zinc-Strontium Alloys
A. F. Cipriano ¹ , A. Sallee¹, R. Guan², H. Liu ^1
1 University of California, Riverside, Riverside, CA, ²Northeastern University, Shenyang, China

879. A Novel Metallic Scaffold that Promotes the Rapid Seeding of Endothelial Cells
M. Shayan ¹ , Y. Chun ^1
1 University of Pittsburgh, Pittsburgh, PA

880. Development of Biodegradable Elastomeric Polyurethanes with Low Initial Moduli
Y. Hong, C. Xu
University of Texas at Arlington, Arlington, TX

881. NaOH-etched PCLTA and mPEGA/PCLTA Networks for Regulating Smooth Muscle Cells
X. Liu , J. Dou, S. Wang, T. Mickens
The University of Tennessee, Knoxville, Knoxville, TN

882. Albumin and Fibrinogen Adsorption, Platelet Adhesion and Activation on ePTFE and Electrospun PTFE
S. Lamichhane ¹ , T. Remund², M. Larson³, P. Kelly⁴, G. Mani ^1
1 University of South Dakota, Sioux Falls, SD, ²Sanford Research, Sioux Falls, SD, ³Augustana College, Sioux Falls, SD, ⁴ Sanford Vascular Associates, Sioux Falls, SD

883. Hyaluronic Acid Modified Surfaces for the Reduction of the Inflammatory Response
J. E. Tengood ¹ , M. Reiss², J. Slee¹, B. Purcell², S. Caliari², R. J. Levy¹, J. Burdick², S. Stachelek ^1
1 Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA

884. Fabrication and Characterization of Endothelialized Elastic Hollow Fiber Membranes as Small Diameter Vascular Grafts
A. E. Mercado Pagan , A. M. Stahl, M. Ramseier, A. Behn, Y. Yang
Stanford University, Stanford, CA

885. Fabrication of Human Serum Albumin Nano Films for Enhanced Hemocompatibility and Smooth Muscle Cell Response.
A. Khanna , R. Burtovvy, M. LaBerge
Clemson University, Clemson, SC