Advanced Antimicrobial Materials

10:30 a.m. 281. Bacteriophage Encapsulation in Poly(Ethylene Glycol) Hydrogels Significantly Reduces Bacteria Numbers in an Implant-Associated Infection Model of Bone Repair, C. T. Johnson*(1), N. Dinjaski(2), M. Auxiliadora Prieto(2), A. J. Garcia(1), (1)Georgia Institute of Technology, Atlanta, GA, (2)Consejo Superior de Investigaciones Cientificas, Madrid, Spain

10:45 a.m. 282. Tunable Antibacterial Gellan Hydrogels for Burn Wounds, S. Shukla*, A. Shukla, Brown University, Providence, RI

11:00 a.m. 283. Click Chemistry and Implantable Biomaterial for Local Enhancement of Systemic Small Molecules, J. M. Mejia Oneto*(1), M. Gupta(1), J. K. Leach(2), L. Lindsay(2), J. Sykes(2), M. Royzen(3), (1)University of California, Davis Medical Center, Sacramento, CA, (2)University of California, Davis, Davis, CA, (3)University at Albany, Albany, NY

11:15 a.m. 284. Platelet Adhesion and Bacterial Adhesion on PEG-Modified Textured Biomaterial Surfaces, L. Xu*, C. A. Siedlecki, Penn State University, Hershey, PA

11:30 a.m. 285. Chitosan Immobilized Titanium Surface in Co-Culture System, B. Foss*(1), Y. Sun(2), Y. Deng(1), (1)The University of South Dakota, Sioux Falls, SD, (2)University of Massachusetts-Lowell, Lowell, MA

11:45 a.m. 286. Surface Modification by Antibiotic-Loaded Microgels Inhibits Bacterial Colonization, J. Liang, Y. Wu, M. Libera*, Stevens Institute of Technology, Hoboken, NJ

12:00 p.m. 287. Ionic Liquids Deliver Antibiotic Into Skin and Neutralize Biofilm-Protected Pathogens, M. Zakrewsky*(1), K. S. Lovejoy(2), T. L. Kern(2), T. E. Miller(2), V. Le(1), A. Nagy(2), A. M. Goumas(2), R. S. Iyer(2), R. E. Del Sesto(3), A. T. Koppisch(4), D. T. Fox(2), S. Mitragotri(1), (1)University of California Santa Barbara, Santa Barbara, CA, (2)Los Alamos National Laboratory, Los Alamos, NM, (3)Dixie State University, St. George, UT, (4)Northern Arizona University, Flagstaff, AZ

12:15 p.m. 288. Removal of Drug-Resistant Bacteria and Ebola Virus from Whole Blood with a Sorbent Hemoperfusion Device: Carbapenum-Resistant Enterobacteriaceae, R. S. Ward*, K. M. McCrea, ExThera Medical Corporation, Berkeley, CA

Biomaterials for Cardiovascular Regeneration

10:30 a.m. 289. Micropatterning Directional Extracellular Matrix Cues in Hydrogel-based Scaffolds for Cardiac Tissue Engineering, Q. Jallerat*, V. S. Palayekar, A. W. Feinberg, Carnegie Mellon University, Pittsburgh, PA

10:45 a.m. 290. Single-step Chemistry to Independently Control Matrix Stiffness and Conjugation of Pro-angiogenic Peptides, L. Cai*, S. Heilshorn, Stanford University, Stanford, CA

11:00 a.m. 291. Sequential Delivery of VEGF165 and PDGF-BB to Repair Myocardial Infarction, H. K. Awada*, Y. Wang, University of Pittsburgh, Pittsburgh, PA

11:15 a.m. 292. Biomimetic Micropatterns Based on the Embryonic Heart for 2D Cardiac Tissue Engineering, I. Batalov*, S. Kim, Q. Jallerat, A. W. Feinberg, Carnegie Mellon University, Pittsburgh, PA

11:30 a.m. 293. Hydrogels to Support 3D Microvessel Formation by Blood-derived Endothelial Progenitor Cells, E. Brown Peters*(1), N. Christoforou(2), K. W. Leong(3), G. A. Truskey(1), J. L. West(1), (1)Duke University, Durham, NC, (2)Duke University, Khalifa University, Abu Dhabi, United Arab Emirates, (3)Duke University, New York City, NY

11:45 a.m. 294. Assessing the Calcification Potential of Engineered Vascular Grafts with Surface Enhanced Raman Spectroscopy, K. R. Kerney*, N. Roki, M. Fenn, C. Bashur, Florida Institute of Technology, Melbourne, FL

12:00 p.m. 295. Promoting Neonatal Cardiomyocyte Proliferation using a Cryptic Matrikine Derived from Fibrillin-1, K. J. Edmunds(1), J. S. Weinbaum(2), L. D. Black, III*(1), (1)Tufts University, Medford, MA, (2)University of Pittsburgh, Pittsburgh, PA

12:15 p.m. 296. Temporal Regulation of GSK3/Wnt Signaling Molecules within a 3D Gelatin/chitosan Scaffold Promoting Cardiac Differentiation of Amniotic Fluid Derived Induced Pluripotent Stem Cells for Congenital Heart Defect Repair, C. Tsao*, S. Pok, A. Velasquez-Mao, J. Jacot, Rice University, Houston, TX

Injectable Biomaterials for Tissue Regeneration

10:30 a.m. 302. Injectable Gelatin Derivative Hydrogels with Sustained Vascular Endothelial Growth Factor Release for Induced Angiogenesis, Z. Li*, Texas A&M University Baylor College of Dentistry, Dallas, TX

10:45 a.m. 303. In Situ Cross-linkable Gelatin Hydrogels for Vasculogenic Delivery of Mesenchymal Stem Cells, S. H. Lee*(1), Y. Lee(2), P. P. Young(3), K. D. Park(2), H. Sung(1), (1)Vanderbilt University, Nashville, TN, (2)Ajou University, Suwon, Republic of Korea, (3)Vanderbilt University Medical Center, Nashville, TN

11:00 a.m. 304. Injectable Dual-Crosslinking Hydrogels to Decouple Material Retention and Mechanical Properties In Vivo, C. B. Rodell*(1), J. W. MacArthur, Jr.(2), R. J. Wade(1), S. M. Dorsey(1), J. A. Burdick(1), (1)University of Pennsylvania, Philadelphia, PA, (2)University of Pennsylvania School of Medicine, Philadelphia, PA

11:15 a.m. 305. Smooth Muscle Cells on Photo-cured Poly(epsilon-caprolactone) Substrates with Varied Stiffness and Micro-grooves, J. Dou*, S. Wang*, The University of Tennessee, Knoxville, Knoxville, TN

11:30 a.m. 306. Subretinal Injection of Micropatterned Nanosheets for Effective Cell Delivery, H. Kaji*(1), Y. Mori(1), T. Fujie(2), N. Nagai(1), T. Abe(1), (1)Tohoku University, Sendai, Japan, (2)Waseda University, Tokyo, Japan

11:45 a.m. 307. Strong Injectable Thermosensitive Scaffolds for Cell Therapy, C. Ceccaldi*, E. Assaad, L. Bonneton, S. Lerouge, Laboratory of Endovascular Biomaterials (LBeV), cole de technologie suprieure (ETS) / CHUM Research Center (CRCHUM), Montral, QC, Canada., Montral, QC, Canada

12:00 p.m. 308. Injectable Microporous Scaffolds from Annealed Building Blocks for Accelerated Wound Healing, D. R. Griffin*, W. M. Weaver, P. Scumpia, D. DiCarlo, T. Segura, UC Los Angeles, Los Angeles, CA

12:15 p.m. 309. Mineralization and Bone Regeneration of Injectable, Dual-Gelling Hydrogel-Cell Constructs, T. N. Vo*, S. R. Shah, S. Lu, E. J. Lee, A. M. Tatara, A. G. Mikos, Rice University, Houston, TX

Mechanical Characterization of Biomaterials

10:30 a.m. 310. Tensile Mechanical Property Evaluation of Two Absorbable Sutures: Effects of Size and Types, N. Daversa, D. Burkley, L. Vailhe, M. Deng*, Ethicon, Somerville, NJ

10:45 a.m. 311. Experimental and Computational Study of Process-Property Relationships for Bioabsorbable Polymers, C. R. Gajjar*(1), B. Singhi(2), M. A. Pasquinelli(2), M. W. King(1), (1)North Carolina State University, Raleigh, NC, (2)NCSU, Raleigh, NC

11:00 a.m. 312. Strengthening of Ti-6Al-7Nb Alloy for Dental Narrow Implants, T. Hanawa*(1), M. Ashida(1), P. Chen(1), H. Doi(1), Y. Tsutsumi(1), Z. Horita(2), (1)Tokyo Medical and Dental University, Tokyo, Japan, (2)Kyushu University, Fukuoka, Japan

11:15 a.m. 313. Improving Fatigue and Fracture Resistance of 45S5 Bioactive Glass/Polyurethane Biocomposites for Repairing Bone Defects, A. J. Harmata*, S. Uppuganti, M. Granke, S. A. Guelcher, J. S. Nyman, Vanderbilt University, Nashville, TN

11:30 a.m. 314. Tailoring the Mechanical Characteristics of PEG-based Hydrogels for the Production of High-performance Soft Tissue Expander, m. jamadi khiabani*(1), P. shokrollahi(2), b. houshmand(3), m. daliri(4), (1)National Institute of Genetic Engineering and Biotechnology, Tehran, Iran, (2)Iran Polymer and Petrochemical Institute, Tehran, Iran, (3)Shahid Beheshti University of Medical Sciences, Tehran, Iran, (4)Animal biotechnology department, National Institute of Genetic Engineering and Biotechnology, tehran, Iran

11:45 a.m. 315. Burst Properties and Adhesion Strength of Oxidized Methacrylated Alginate Lung Sealants, P. Charron*, A. Poniz, S. Fenn, D. Weiss, R. Oldinski, University of Vermont, Burlington, VT

12:00 p.m. 316. Relevance of the Spatial Distribution Pattern of Mechanical Properties of Articular Cartilage in Animal Studies, S. Sim(1), I. Hadjab(1), M. Garon*(2), E. Quenneville(2), M. D. Buschmann(1), (1)Ecole Polytechnique de Montreal, Montreal, QC, Canada, (2)Biomomentum Inc., Laval, QC, Canada

12:15 p.m. 317. Characterization of Soft Tissue Transmural Microstructure, J. G. Lesicko*, K. R. Feaver, M. S. Sacks, The University of Texas at Austin, Austin, TX

PANEL DISCUSSION: Cardiovascular Device Development and the Regulatory Process

297. Chirag Tilara, Medtronic, Inc.

298. Emily Ho, Secant Medical

299. Semih Oktay, CardioMed Device Consultants

300. Craig Weinberg, Biomedical Device Consultants and Laboratories

301. Paul Schmidt, Edwards Lifesciences

Recent Advances in Surface Modication of Biomaterials 2

10:30 a.m. 318. Surface Modification of Ceramic Biomaterials After in vivo Exposure to the Physiological Environment, A. Wusylko, K. Kornev, M. Harman*, Clemson University, Clemson, SC

10:45 a.m. 319. Biological Tethering of N-Cadherin to Substrates Promotes Cell-Cell Adhesion, J. Vega, M. K. Lee*, D. E. Leckband, H. Kong, UIUC, Urbana, IL

11:00 a.m. 320. Organic-Inorganic Hybrid Coating for Deformable and Biioactive Magnesium Implants, G. Cheon*, J. Song*, S. Kim, M. Kang, H. Kim, Seoul National University, Seoul, Republic of Korea

11:15 a.m. 321. Glow-Discharge RF Plasma Polyether and Fluoropolyether Substrates Prevent Protein Adsorption, M. Mecwan*, B. Ratner, University of Washington, Seattle, WA

11:30 a.m. 322. Rapid Coating of AZ31 Magnesium Alloy with Calcium Deficient Hydroxyapatite Using Microwave Energy, Y. Ren*, H. Zhou, S. Bhaduri, The University of Toledo, Toledo, OH

11:45 a.m. 323. Bioinspired Hydrogels for Transfer Printing of Ultracompliant Medical Electronics, H. Wu*, C. Zhu, C. Bettinger, Jr., Carnegie Mellon University, Pittsburgh, PA

12:00 p.m. 324. Life-long Durability of Orthopedic Bearings by Phospholipid Polymer Grafting and Antioxidant Blending, M. Kyomoto*, T. Moro, S. Yamane, K. Watanabe, K. Ishihara, The University of Tokyo, Tokyo, Japan

12:15 p.m. 325. Hydroxyapatite/poly(ether imide) Micro-patterned Protective Coating on Magnesium for Biomedical Applications, S. Kim*, J. Song, M. Kang, G. Chun, H. Kim, Seoul National University, Seoul, Republic of Korea

Small Molecule Drug Delivery

10:30 a.m. 326. Sustained Release of Short Peptides Using Guest-host Complex Formation in Injectable Hydrogels, J. E. Mealy*(1), C. B. Rodell(1), J. A. Burdick(2), (1)University of Pennsylvania, Philadelphia, PA, (2)University of Pennsylvania, University of Pennsylvania, PA

10:45 a.m. 327. PEG Hydrogel Nanoparticles for Controlled Release of Angiogenic Peptides, D. A. Young*, G. Papavasiliou, Illinois Institute of Technology, Chicago, IL

11:00 a.m. 328. Synthesis of Protein-polymer Conjugates with Controllable Properties, H. Chen*, L. Wang, X. Li, L. Yuan, H. Wang, G. Chen, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, China

11:15 a.m. 329. Injectable in situ Forming Depot Systems for Long Acting Contraception, D. R. Janagam*, L. Wu, K. Chaudhry, T. D. Mandrell, J. R. Johnson, T. L. Lowe, University of Tennessee Health Science Center, Memphis, TN

11:30 a.m. 330. Design and Construction of Hypoxically Activated Drug Release System, Y. Ikeda*, H. Hisano, Y. Nagasaki, University of Tsukuba, Tsukuba, Japan

11:45 a.m. 331. Gap Junction Liposomes for Direct Therapeutic Delivery to the Cellular Cytoplasm, D. J. Busch*, J. Stachowiak, University of Texas at Austin, Austin, TX

12:00 p.m. 332. Amorphous Magnesium Phosphate Nanoparticles as Nonviral DNA Carriers, M. Nabiyouni*, S. B. Bhaduri, University of Toledo, Toledo, OH

12:15 p.m. 333. Scaffolds with Incorporated Photo-Carbon Monoxide Releasing Materials for Engineering Vascular Grafts, E. K. Michael*, N. Abeyrathna, K. Birthare, Y. Liao, C. Bashur, Florida Institute of Technology, Melbourne, FL

Stem Cell and Biomaterial Interactions 2

10:30 a.m. 334. Towards Engineering a Multi-Niche Functional Human Bone Marrow: Advancing Basic Studies and Aiding Clinical Translation, M. R. Nelson*(1), K. Bai(2), K. Roh(1), K. Roy(1), (1)Georgia Institute of Technology and Emory University, Atlanta, GA, (2)Georgia Institute of Technology, Atlanta, GA

10:45 a.m. 335. 3D Stem Cell Morphotyping of Tissue Engineering Scaffold Niches, S. J. Florczyk*, M. Simon, D. Juba, S. Sarkar, D. Chen, P. J. Baker, A. Cardone, M. Brady, P. Bajcsy, C. G. Simon, Jr., National Institute of Standards and Technology, Gaithersburg, MD

11:00 a.m. 336. Eliminating Dexamethasone from Osteogenic Media Leads to the Production of Angiogenic Factors by Microencapsulated Adipose Stem Cells, S.K. Leslie*, Z. Schwartz, B. D. Boyan, Virginia Commonwealth University, Richmond, VA

11:15 a.m. 337. Multivalent Platform for Spatial Control of Arterial Venous Differentiation of Pluripotent Stem Cells, T. B. Dorsey*, G. Dai, Rensselaer Polytechnic Institute, Troy, NY

11:30 a.m. 338. Polyethylene Glycol Hydrogels Functionalized with a Continuous Ile-Lys-Val-Ala-Val Concentration Gradient for Optimizing Neural Differentiation of Murine Embryonic Stem Cells in 2D, L. Smith Callahan*(1), H. Yang(2), (1)University of Texas Health Science Center, Houston, TX, (2)University of Texas Health Science Center at Houston, Houston, TX

11:45 a.m. 339. Bioinstructive Scaffolds Through a Multiscale Approach Mimicking Tissue Mechanics and Regulating Differentiation, B. L. Banik*(1), J. L. Brown(2), (1)The Pennsylvania State University, State College, PA, (2)The Pennsylvania State University, University Park, PA

12:00 p.m. 340. Maintaining the Pluripotency of Mouse Embryonic Stem Cells on Gold Nanoparticle Layers with Nanoscale but not Microscale Surface Roughness, Z. Lyu*, The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, P. R. China., Suzhou, China

12:15 p.m. 341. Electric Field Induced Lineage Commitment of Mesenchymal Stem Cells Towards Neural-like Cells on Conducting Polyaniline Substrates, G. Thrivikraman*, G. Madras, B. Basu, Indian Institute of Science, Bangalore, India