Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Harborside Ballroom A-B, 4th Floor
About
Treatment of microbial infections is complicated by rising antibiotic resistance and the inherent difficulty of treating biofilm-associated infections. In both scenarios, many current FDA approved antimicrobial drugs are ineffective, leading to a significant health and economic burden. Compounding these issues is a lack of development of new antimicrobial drug classes limiting the pipeline of available therapeutics. Advances in antimicrobial biomaterial therapies have the potential to improve outcomes for bacterial, fungal, viral, and biofilm-associated infections. Innovations in biomaterials are critically needed in the face of the COVID-19 pandemic, both for treatments of the SARS-CoV-2 virus, and also for effective treatment of the severe bacterial and fungal co-infections that have been reported. This session will cover biomaterials approaches to treat bacterial, fungal, and viral infections, including the prevention and eradication of biofilms. Strategies discussed may include antimicrobial surface modifications, device coatings, drug delivery, and immune engineering approaches.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 323. INVITED SPEAKER - Christopher A. Alabi, PhD, Cornell University
11:00:00 324. Prevention of Medical Device Infections via Multi-action Nitric Oxide and Chlorhexidine Diacetate Releasing Medical Grade Silicone Biointerfaces, Elizabeth Brisbois*, Manjyot Kaur Chug, Hamed Massoumi, University of Georgia, Athens, GA, USA
11:15:00 AM 325. Biphasic Dressings for Effective Treatment of Biofilms in Chronic Wounds, Jingwei Xie*, Yajuan Su, Guangshun Wang, University of Nebraska Medical Center, Omaha, NE, USA
11:30:00 AM 326. Enzymatically-Responsive Shape Memory Polymers for Infection Surveillance in Chronic Wounds, Maryam Ramezani, PhD*, Avery Gunderson, Mary Beth Monroe, PhD, Syracuse University, Syracuse, NY, USA
11:45:00 AM 327. Drug-Eluting Endotracheal Tubes for Microbiome Modulation in Murine Airway Models, Matthew Aronson(1,2)*, Ryan Friedman(1,2), Daniel Ghaderi(1,2), Riccardo Gottardi(1,2,3); (1)University of Pennsylvania, Philadelphia, PA, USA, (2)Children’s Hospital of Philadelphia, Philadelphia, PA, USA, (3)Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
12:00:00 PM 328. Oxygenating and antibacterial MACF hydrogel dressings reduce infection on an infected diabetic wound model, Hannah Durr*, Shahrzad Abri, MS, Nic Leipzig, PhD, University of Akron, Akron, OH, USA
12:15:00 PM 329. Lysostaphin-loaded hydrogels mitigate chronic S. aureus infection in non-union bone defects, Pranav Kalelkar, PhD*, Andres Garcia, PhD, Georgia Institute of Technology, Atlanta, GA, USA
Attachments
Invited Speaker(s)
Biomaterials for Pancreatic Islet Replacement and Immune Tolerance in T1D-2
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Kent A-C, 4th Floor
About
The advent of new sources of beta cells, including from stem cells, has greatly advanced the potential of beta cell replacement as a functional cure for type 1 diabetes and some forms of type 2 diabetes. A major barrier that remains to be solved is blocking or modulating immune effectors while simultaneously promoting islet survival and function. Biomaterials play a central role in addressing this challenge, as vehicles for islet delivery, as microenvironments supportive of islet function, and as sites of immune modulation.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 330. INVITED SPEAKER - Cellular engineering to produce replace- ment islets for diabetes cellular therapy, Jeffrey Millman, PhD, Washington University School of Medicine
11:00:00 AM 331. Injectable PEG-MAL Hydrogel Based on Guest-Host Interlinked PEG Microgels, Adrienne Widener*, Jorge Santini-Gon- zalez, Conor Given, Thomas Angelini, PhD, Edward Phelps, PhD, University of Florida, Gainesville, FL, USA
11:15:00 AM 332. Synthetic Hydrogel-mediated Maturation and Engraftment of Human Pluripotent Stem Cell-derived Beta Cells, Michael Hunckler*, Maria Coronel, Adriana Mulero-Russe, Andrés García, Georgia Institute of Technology, Atlanta, GA, USA
11:30:00 333. In Vitro Hydrogel Platform for the Interrogation of the Role of Chemokines in Human T1D Immunopathology, Magdalena Samojlik, MS(1)*, Ying Li, PhD(1,2), Smit Patel(1), Aidan Fernandez(1), Todd Brusko, PhD(2), Clayton Mathews, PhD(2), Edward Phelps, PhD(1), Cherie Stabler, PhD(1); (1)University of Florida, College of Engineering, Gainesville, FL, USA, (2)University of Florida, College of Medicine, Gainesville, FL, USA
11:45:00 AM 334. CCL21 and Beta Cell Antigen Hydrogel Platform for Induction of Antigen-Specific Tolerance in Type 1 Diabetes, Flavia Zisi Tegou, MS(1,2)*, Diana Velluto, PhD(2), Aaron Stock, PhD(1,2), Silviya Zustiak, PhD(3), Alice Tomei, PhD(1,2); (1)University of Miami, Coral Gables, FL, USA, (2)Diabetes Research Institute, Miami, FL, USA, (3)Saint Louis University, Saint Louis, MO, USA
12:00:00 PM 335. Microporous Scaffolds for Culture and Transplantation of Stem Cell Derived Beta-Cells, Kelly Crumley*, Elizabeth Bealer, Feiran Li, Daniel Clough, PhD, Lonnie Shea, PhD, University of Michigan, Ann Arbor, MI, USA
12:15:00 PM 336. In Vivo pO2 Measurement of Islet Encapsulation Devices in Oxygen Measurement Core, Mrignayani Kotecha(1)*, Navin Viswakarma(1), Eliyas Siddiqui(1), Safa Hameed(1), Sonny Patel(1), Longhai Wang(2), Alexander Ulrich Ernst(2), Minglin Ma(2), Cherie Stabler(3), Boris Epel(1,4); (1)O2M Technologies, LLC, Chicago, IN, USA, (2)Cornell University, Ithaca, NY, USA, (3)University of Florida, Gainesville, FL, USA, (4)The University of Chicago, Chicago, IL, USA
Invited Speaker(s)
Biophysical Strategies for Regulation of Cellular Microenvironments
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Laurel A-B, 4th Floor
About
Biophysical factors directed by biomaterials are known to play important roles in regulating cellular behavior by influencing gene and protein expression, protein localization, and cell signaling activity. This session focuses on biomaterial-based strategies for regulating biophysical factors in engineered cellular microenvironments. Topics include but are not limited to novel uses of biomaterials for regulation of nano- and micro-topographical and ligand patterning cues, normal and shear stress environments, thermosensitive properties, and physical parameters of fiber networks for regulating cellular phenotype. This includes studies incorporating novel strategies for control of biophysical parameters in biomaterial design for engineering of physiological models as well as fundamental studies of the mechanisms by which cells utilize biophysical cues from the biomaterials in their microenvironment to elicit specific biological outcomes. The studies presented in this session will contribute to the design of next-generation biomaterials capable of precisely and predictably directing cellular behaviors.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 337. Extracellular Matrix in Hydrogel-based Organoids Regulate Epigenetics and Signaling in Prostate Cancers, Ankur Singh(1)*, Matthew Mosquera(2), Ahmet Coskun(1), Zhou Fang(1), Shuangyi Cai(1), Sungwoong Kim(1), Olivier Elemento(3); (1)Georgia Insti- tute of Technology, Atlanta, GA, USA, (2)Cornell University, Ithaca, NY, USA, (3)Weill Cornell Medicine, New York, NY, USA
10:45:00 AM 338. Influence of Interpenetrating Network Viscoelasticity on Cellular Infiltration, Karen Xu*, Jason Burdick, PhD, University of Pennsylvania, Philadelphia, PA, USA
11:00:00 AM 339. Synthetic semi-IPN hydrogels with fast stress-relaxation to probe stromal-cancer interactions, Fang-Yi Lin, PhD, Chien-Chi Lin, PhD*, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA
11:15:00 AM 340. Biomimetic Proteoglycans Augment the Cellular Microniche of Chondrocytes in Articular Cartilage, Elizabeth Kahle(1)*, Biao Han, PhD(1), Prashant Chandrasekaran, PhD(1), Evan Phillips, PhD(1), Katsiaryna Prudnikova, PhD(1), Lin Han, PhD(1), Michele Marcolongo, PhD, PE(1,2); (1)Drexel Uni- versity, Philadelphia, PA, USA, (2)Villanova University, Villanova, PA, USA
11:30:00 AM 341. Stretchable Collagen I Hydrogels Reverse Pro-Fibrotic Transcriptome of Senescent Fibroblasts, Jason Guo, PhD*, Michelle Griffin, MD, PhD, Nicholas Guardino, BS, Kellen Chen, PhD, Geoffrey Gurtner, MD, FACS, Michael Longaker, MD, MBA, FACS, Stanford University School of Medicine, Stanford, CA, USA
11:45:00 AM 342. Cell-Mimetic Substrates Reprogram Collective Cell Behaviors, Elena Cho, Kevin Suh, Isaac Breinyn, Daniel Cohen, PhD*, Princeton University, Princeton, NJ, USA
12:00:00 PM 343. Photopatterning Facilitates Deterministic Crypt Formation in iPSC-Derived Intestinal Organoids, Michael Blatchley, PhD(1)*, Max Yavitt(1), Jasmine LeFevre(1), Patrick McGrath, PhD(2), Peter Dempsey, PhD(2), Kristi Anseth, PhD(1); (1)University of Colorado - Boulder, Boulder, CO, USA, (2)University of Colorado School of Medicine, Aurora, CO, USA
12:15:00 PM 344. Modeling Acoustic Radiation Forces in Hydrogels using 3D Force Microscopy, Kevin Grassie(1,2)*, Hanna Anderson(1,2), Fayekah Assanah, PhD(1), Will Linthicum, PhD(1), Bryan Huey, PhD(1), Yusuf Khan, PhD(1,2); (1)University of Connecticut, Storrs, CT, USA, (2)UConn Health, Farmington, CT, USA
Drug Delivery 3 (SIG)
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Harborside Ballroom D-E, 4th Floor
About
The Drug Delivery SIG session will consider abstracts that fall with the broad areas of therapeutic development, formulation, and application testing. Drug delivery from medical devices, tissue engineering scaffolds/hydrogels, films, microparticles, nanoparticles, environmentally responsive materials, and other types of biomaterial assemblies are all invited. Studies testing drug targeting, drug combinations, and drug/cell combinations are all also welcomed to submit. Drug delivery application areas of interest include but are not limited to regenerative medicine/tissue engineering, cell and tissue transplant, cardiovascular stents and other devices, cancer, microbial infection, and autoimmune diseases.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 345. Biodegradable Nanogels for Controlled Release of Artemisinin-de- rived Drug to Treat Leukemia, Noha Ghonim(1)*, Sumiya Tabassum(2), Bryan Mott(3), Rena Lapidus(4), Michelle Rudek(5), Curt Civin(4), Tao Lowe(1); (1)School of Dentistry, University of Maryland Baltimore, Baltimore, MD, USA, (2)Health Sciences Facility II , University of Maryland Baltimore, Baltimore, MD, USA, (3)Wake Forest Baptist Medical Center, Winston-Salem, NC, USA, (4)School of Medicine, University of Maryland Baltimore, Baltimore, MD, USA, (5)School of Medicine, Johns Hopkins University, Baltimore, MD, USA
10:45:00 AM 346. Hydroxycholesterol Substitution in Ionizable Lipid Nanoparticles for mRNA Delivery to T Cells, Savan Patel*, Margaret Billingsley, Caitlin Frazee, Xuexiang Han, PhD, Kelsey Swingle, Michael Mitchell, PhD, University of Pennsylvania, Philadelphia, PA, USA
11:00:00 AM 347. Multi-step Screening and Composition Optimization of Lipid Nanoparticles for Liver-targeted Plasmid DNA Delivery, Yining Zhu(1)*, Ruochen Shen(1), Ivan Vuong(1), Hai-Quan Mao, PhD(1), Rebekah Reynolds, PhD(2), Melanie Shears, PhD(2), Sean Murphy, PhD(2); (1)Johns Hopkins University, Baltimore, MD, USA, (2)University of Washington, Seattle, WA, USA
11:15:00 AM 348. Engineering nanoparticle surface chemistry to maximize lymph node delivery via lymphatic vessels, Jacob McCright*, Colin Skeen, Jenny Yarmovsky, Katharina Maisel, University of Maryland, College Park, MD, USA
11:30:00 AM 349. Biomimetic Membrane-Wrapped Nanoparticles for Targeted Drug Delivery to Hematopoietic Stem and Progenitor Cells, Jenna Harris(1)*, Emily Day(1,2); (1)University of Delaware, Newark, DE, USA, (2)Helen F. Graham Cancer Center & Research Institute, Newark, DE, USA
11:45:00 AM 350. Design, characterization, and modeling of a chitosan microneedle patch for transdermal delivery of meloxicam as a pain management strategy for use in cattle, Katherine Miranda Munoz*, David Castilla Casadiego, PhD, Jeremy Powell, PhD, Jorge Almodovar, PhD, University of Arkansas, Fayetteville, AR, USA
12:00:00 PM 351. Mineral Coated Microparticles for Stabilization of Therapeutic Messenger RNA, Joshua Choe, MS*, William Murphy, PhD, University of Wisconsin - Madison, Madison, WI, USA
12:15:00 PM 352. Continuous Manufacturing of Liposomes and Lipid-based Nanoparticles, Antonio Costa, PhD.(1)*, Xiaoming Xu(2), Gowtham Yenduri(3), Thomas O’Connor(2), Hailing Zhang(2), Diane Burgess(3); (1)DIANT PHARMA INC., Storrs, CT, USA, (2)FDA, Silver Spring, MD, USA, (3)University of Connecticut, Storrs, CT, USA
Engineering Cells and Their Microenvironments 2 (SIG)
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Essex A-C, 4th Floor
About
The Engineering Cells & Their Microenvironments Special Interest Group focuses on approaches to alter cell microenvironments. These approaches can be used to control biomaterial-induced cell signaling to enable stem cell manufacturing and differentiation, immunoengineering, as well as for the development of biomaterials for cell-based detection and diagnosis. These biomaterial-based approaches can also be utilized to direct cellular responses (e.g., proliferation, differentiation, morphological regulation, motility, matrix production) without the addition of external growth factors, chemicals, or drugs, thereby mitigating potential side-effects and facilitating improved in vitro and in vivo cellular outcomes. This session will focus on translation of these techniques toward a variety of specific applications ranging from, but not limited to, tissue engineering for dynamic disease models and regenerative medicine to therapeutics and direction of stem cell differentiation. Studies that develop biomimetic materials which provide specific physicochemical cues (e.g., composition, topography, stiffness) to achieve a desired cellular response will also be highlighted.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 353. Multi-Modular Vascularized Bone Construct Comprised of Cell-Laden Microtissues, Nicholas Schott, MEng*, Jan Stegemann, PhD, The University of Michigan, Ann Arbor, MI, USA
10:45:00 AM 354. Gradient hydrogels formed by tandem diffusion and orthogonal click reactions, Chun-Yi Chang(1)*, Chien-Chi Lin(1,2); (1)Purdue University, West Lafayette, IN, USA, (2)Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA
11:00:00 AM 355. Silk Fibroin Hydrogels Mimic Native Matrix Mechanics and Support Salivary Spheroid Development, Eugenia Morales Carrillo(1)*, Solaleh Miar(1), Chih-ko Yeh(2), Joo Ong(1), Teja Guda(1); (1)The University of Texas at San Antonio, San Antonio, TX, USA, (2)University of Texas Health San Antonio, San Antonio, TX, USA
11:15:00 AM 356. Hydrogel Assisted Double Molding of 3D Print Enable Prestress Regulation of Stem Cell Derived Micro Heart Muscle, Daniel Simmons(1)*, David Schuftan(1), Jingxuan Guo(1), Kasoorelope Oguntuyo(1), Ghiska Ramahdita(1), Mary Munsell(1), Evan Miller(2), Nathaniel Huebsch(1); (1)Washington University in St. Louis, St. Louis, MO, USA, (2)University of California, Berkeley, University of California Berkeley, CA, USA
11:30:00 AM 357. Substrate Stiffness Regulates Fibronectin Matrix Microarchitecture During Wound Healing, Jennifer Patten, MS*, Gobind Singh, BS, Karin Wang, PhD, Temple University, Philadelphia, PA, USA
11:45:00 AM 358. Engineering symmetry breaking of single cells in three-dimensional matrices to direct stem cell fate, Ik Sung Cho*, Sing-Wan Wong, Stephen Lenzini, Jae-Won Shin, University of Illinois at Chicago, Chicago, IL, USA
12:00:00 PM 359. A Multi Fluorophore Reporter System for Identification and Quantification of Vomocytosis, Noah Pacifici*, Jamal Lewis, PhD, University of California, Davis, Davis, CA, USA
12:15:00 PM 360. Lentiviral reporters for temporal characterization of cell activation in response to dynamic stimuli, Samantha Cassel*, April Kloxin, PhD, University of Delaware, Newark, DE, USA
Immune Engineering (SIG)
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Laurel C-D, 4th Floor
About
The Immune Engineering SIG deals with engineered biomaterials for the development of immunotherapeutics and immune microenvironment engineering, to uncover fundamental mechanisms of immunobiology, and systems immunology.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 361. Exogenous Delivery of Indoleamine 2,3-Dioxy- genase Reverses Disease Severity in Psoriasis, Sabrina Macias*, Arun Wanchoo, PhD, Gregory Hudalla, PhD, Benjamin Keselowsky, PhD, University of Florida, Gainesville, FL, USA
10:45:00 AM 362. Pro-fibrotic biomaterials implanted after injury skew local and systemic monocyte expression profiles, Joshua Hooks, PhD*, Kavita Krishnan, Patricia Mensah, Christopher Cherry, PhD, Jin Han, PhD, Jennifer Elisseeff, PhD, Johns Hopkins School of Medicine, Baltimore, MD, USA
11:00:00 AM 363. Using high-throughput ELISA protocols to identify seroconversion in adults during the COVID-19 Pandemic, Mondreakest Faust, BS*, Kaitlyn Sadtler, PhD, Maria Karkanitsa, BS, Jacquelyn Spathies, Heather Kalish, NIH (National Institutes for the Health), Bethesda, MD, USA
11:15:00 AM 364. Age-related Immune-Stromal Networks Inhibit Response to Regenerative Immunotherapies, Jin Han, PhD*, Christopher Cherry, PhD, Anna Ruta, B.S., David Maestas, B.S., Joscelyn Mejias, PhD, Helen Hieu Nguyen, B.S., Elana Fertig, PhD, Franck Housseau, PhD, Drew Pardoll, PhD, Jennifer Elisseeff, PhD, Johns Hopkins University, Baltimore, MD, USA
11:30:00 AM 365. Compositional Optimization of Lipid Nanoparticles to Transfect Antigen-Presenting Cells with mRNA In Vivo for Cancer Immunotherapy, Ivan Vuong*, Yining Zhu, Ruochen Shen, Won June Cho, Hai-Quan Mao, Johns Hopkins University, Baltimore, MD, USA
11:45:00 AM 366. Self assembling nanomaterials as defined active immunotherapies against IL1-β-mediated inflammation, Shamitha Shetty, MS*, Yaoying Wu, PhD, Joel Collier, PhD, Duke University, Durham, NC, USA
12:00:00 PM 367. Biodegradable Ionizable Polyesters as Non-Viral Gene Delivery Carriers for Enhanced Transfection of Immune Cells, Atanu Chakraborty, PhD*, Ryan Pearson, PhD, University of Maryland Baltimore, Baltimore, MD, USA
12:15:00 PM 368. PEGylation of Indoleamine 2,3-Dioxygenase for Systemic Immune Regulation, Jennifer Simonovich(1)*, Alexander Kwiatkowski(1), Arun Wanchoo(1), Dorina Avram(2), Benjamin Keselowsky(1); (1)University of Florida, Gainesville, FL, USA, (2)Moffitt Cancer Center, Tampa, FL, USA
Panel Discussion: Translating Engineered Multicellular Living Systems and Cellular Microenvironments
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Waterview Ballroom, Ground Level
About
A multidisciplinary panel focused on translating engineered multicellular systems (EMCeLs) and cellular microenvironments from research ideas to broadly applicable clinical tools. EMCeLS and engineered microenviornments may offer several advantages over conventional in vitro cell culture and animal experiments. While many of these approaches use the same biomaterials and microfabrication techniques, and some have already become commercially available products, there are still biomaterial, cell-related and process-based risks that must be reasonably determined, addressed, and reduced to an acceptable level to facilitate safer translational applications of these technologies. This special panel comprises presentations and a moderated discussion focused on translational considerations. Representatives from academia, industry, regulatory and funding agencies, and standards organizations will discuss advancing technologies out of the lab, commercialization of technologies into products for clinical use, compliance with regulatory requirements, and opportunities for funding.
Abstracts
Abstracts will be available for download on April 27, 2022.
Translation in complex environments, Jennifer Elisseeff, PhD, Johns Hopkins University
Thomas Hartung, MD, Johns Hopkins University
Invited Speaker(s)
Tissue Engineering 2 (SIG)
Timeslot: Saturday, April 30, 2022 - 10:30am to 12:30pm
Room: Dover A-C, 3rd Floor
About
The field of tissue engineering has made significant progress in the last two decades through the development of novel biomaterials and three-dimensional scaffold fabrication methods. Efforts to engineer cell niches to control cell behavior over multiple length scales and precisely guide tissue regeneration have advanced the field. To achieve this, a diverse range of novel technologies have been leveraged, including 3D bioprinting, electrospinning, microfluidics, light-based patterning, and directed assembly, to enable notable progress in controlled release and spatial presentation of biomolecules, organ integration, production of tissue models, single cell-level presentation of microenvironmental cues, and molecular-level control of biomaterial composition. This session will highlight recent trends in novel biomaterials and scaffold development and advanced biofabrication techniques towards the development of sophisticated tool kits for tissue engineers.
Abstracts
Abstracts will be available for download on April 27, 2022.
10:30:00 AM 369. Injectable Granular Hydrogels with Dynamic Covalent Interparticle Adhesion for Enhanced Material Properties, Jason Burdick, Shoshana Weintraub, Victoria Muir*, University of Pennsylvania, Philadelphia, PA, USA
10:45:00 AM 370. Compressive buckling fabrication of 3D cell-laden microstructures, Zhaowei Chen, Nanditha Anandakrishnan, Ying Xu, Ruogang Zhao*, University at Buffalo, SUNY, BUFFALO, NY, USA
11:00:00 AM 371. Influence of Lyophiliza- tion Primary Drying Time and Temperature on Porous Silk Scaffold Fabrication for Biomedical Applications, Jeannine Coburn, PhD*, Alycia Abbott, PhD, Mattea Gravina, Mobin vandadi, Nima Rahbar, Worcester Polytechnic Institute, Worcester, MA, USA
11:15:00 AM 372. Microfluidic Driven Hydrogel Tissue Engineering for Modelling and Digitalizing Complex Biological Phenomena, Carlos Guimarães, MEng(1)*, Luca Gasperini, PhD(1), Rajib Ahmed, PhD(2), Alexandra Marques, PhD(1), Utkan Demirci, PhD(2), Rui Reis, PhD, DSc(1); (1)University of Minho, Guimarães, Portugal, (2)Stanford University, Palo Alto, CA, USA
11:30:00 373. Crosstalk with tissue-engineered blood vessels promotes m2 polarization of macrophages, Beatriz Hernaez Estrada(1,2)*, Edorta Santos-Vizcaino(2,3), Rosa Maria Hernandez(2,3), Kara Spiller(1); (1)Drexel University, Philadelphia, PA, USA, (2)University of the Basque Country (EHU/ UPV), Vitoria-Gasteiz, Spain, (3)CIBER BBN, Biomedical Research Networking, Vitoria Gasteiz, Spain
11:45:00 374. Immune-isolating Properties of Poly-ethylene Glycol-based Capsules Protect Human Ovarian Xenografts from Immune Rejection After Six Weeks, Margaret Brunette*, Monica Wall, Marilia Cascalho, PhD, Ariella Shikanov, PhD, University of Michigan, Ann Arbor, MI, USA
12:00:00 PM 375. Dynamic Provisional Matrix Colloidal-Composite Scaffolds for Partial Anterior Cruciate Ligament Tears, Grant Scull(1,2)*, Jacob Thompson(1,2), Seema Nandi, PhD(1,2), Matthew Fisher, PhD(1,2), Ashley Brown, PhD(1,2), Lauren Schnabel, DVM, PhD(2); (1)The Joint Department of Biomedical Engineering at UNC-Chapel Hill and NC State University, Raleigh, NC, USA, (2)North Carolina State University, Raleigh, NC, USA
12:15:00 PM WITHDRAWN