Con-current Oral Abstract Presentations Session 5

Friday, April 23, 2010, 11:30 am - 1:00 pm

Biomaterials as Stem Cell Niche

189

Actin and SRF transduce physical cues from the microenvironment to regulate keratinocyte terminal differentiation

J. T. Connelly, J. E. Gautrot, D. W. Tan, B. Trappmann, W. T. S. Huck, F. M. Watt;

Univ. of Cambridge, Cambridge, UNITED KINGDOM.

190

Microsphere-Mediated Delivery of Retinoic Acid to Embryoid Bodies Induces Spatially Controlled Differentiation

R. L. Carpenedo, S. A. Seaman, A. M. Bratt-Leal, N. J. Bowen, J. F. McDonald, T. C. McDevitt;

Georgia Inst. of Technology, Atlanta, GA.

191

Pluripotent and Vascular Stem Cell Responses to Oxygen Depletion

R. E. Truitt, H. E. Abaci, G. Drazer, S. Gerecht;

Johns Hopkins Univ., Baltimore, MD.

192

Three-dimensional Co-culture in Micropatternable Hydrogels with Cell-Release Capabilities

T. M. Hammoudi, N. C. Bloodworth, H. Lu, J. S. Temenoff;

Georgia Inst. of Technology, Atlanta, GA.

193

Proteoglycan sequestration provides spatially modulated mesenchymal stem cell proliferation

G. A. Hudalla, J. T. Koepsel, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.

194

Tumor Microenvironmental Cues Signal Host Tissue Progenitor Cells to Promote Tumorigenesis

E. M. Chandler, B. Seo, J. S. Lee, C. M. Berglund, B. J. Kirby, C. Fischbach;

Cornell Univ., Ithaca, NY.

Advances in Ophthalmic Biomaterials Technology

195

Causes of Intraocular Lens Opacification or Discoloration: Analyses of Explants

L. Werner;

John A. Moran Eye Ctr., Univ. of Utah, Salt Lake City, UT.

196

Sphere-Templated Polymer Scaffolds for Engineered Synthetic Cornea

S. Garty1, F. I. Simonovsky1, E. Lopez1, S. Kanayama2, T. T. Shen2, B. D. Ratner1;

1Bioengineering, Univ. of Washington, Seattle, WA, 2Ophthalmology, Univ. of Washington, Seattle, WA.

197

Sphere Templated Angiogenic Regeneration (STAR) Biomaterials for Ophthalmic Applications

A. J. Marshall1, S. Garty2, S. Kanayama2, T. T. Shen2, B. D. Ratner2, C. Woods3, M. G. Maginness1;

1Healionics, Seattle, WA, 2Univ. of Washington, Seattle, WA, 3TR Bio, Chandler, AZ.

198

Controlled and Sustained Delivery of AG1478 for Optic Nerve Regeneration

R. Robinson1, J. Lin2, C. A. Williams1, J. M. Criscione1, S. R. Viviano2, J. C. Tsai2, E. B. Lavik3;

1Yale Univ., New Haven, CT, 2Yale Univ. Sch. of Med., New Haven, CT, 3Case Western Reserve Univ., Cleveland, OH.

199

Super-hydrophilic Silicone Hydrogels with Phospholipid Polymer IPN for Newly Contact Lenses

K. Ishihara, T. Shimizu;

The Univ. of Tokyo, Tokyo, JAPAN.

200

Glistenings in Intraocular Lenses

L. Werner;

John A. Moran Eye Ctr., Univ. of Utah, Salt Lake City, UT.

Cellular Responses to Biomaterials and Cardiopathologies

201

Hyperglycemia amplifies the osteogenic responses in vascular cells in the presence of elastin degradation products and TGF-β1

A. Sinha;

Clemson Univ., Clemson, SC.

202

Correlative Light and Electron Microscopy to Determine the Fate of Polyelectrolytes in Porcine Arteries

M. Sandros, M. Tabrizian;

McGill Univ., Montreal, QC, CANADA.

203

Effects of Polymer Degradation on Smooth Muscle Cell Phenotype: Implications for Stent Design

L. S. Sefcik1, B. R. Wamhoff2;

1Lafayette Coll., Easton, PA, 2Univ. of Virginia, Charlottesville, VA.

204

Evaluation of a degradable polar hydrophobic ionic polyurethane designed for vascular graft generation in an in vitro endothelial and monocyte cell co-culture

S. M. McDonald1, L. A. Matheson1, J. E. McBane2, S. Sharifpoor2, J. P. Santerre2, R. S. Labow1;

1Univ. of Ottawa Heart Inst., Ottawa, ON, CANADA, 2Univ. of Toronto, Toronto, ON, CANADA.

205

A Competitive Co-culture Study on Vascular Cell Responses to Underlying Stent Topography

J. Lu, T. J. Webster;

Brown Univ., Providence, RI.

206

Proliferation and Phenotype of Human Coronary Artery Smooth Muscle Cells in Polyurethane Porous Scaffolds under Cyclic Mechanical Strain

S. Sharifpoor1, J. E. McBane1, C. A. Simmons1, R. S. Labow2, J. P. Santerre1;

1Univ. of Toronto, Toronto, ON, CANADA, 2Univ. of Ottawa, Ottawa, ON, CANADA.

Chemoselective Chemistry for Biomaterials

207

Cylic Thioester-Containing Macromonomers for Cross-Linking of Hydrogels by Native Chemical Ligation

J. Su1, B-H. Hu2, P. B. Messersmith1;

1Northwestern Univ., Evanston, IL, 2Hainan Univ., Haikou,Hainan Province, CHINA.

208

Facile C-terminal Attachment of Proteins on Surfaces by Hydrazine-Intein Chemical Reaction

P. Yang, S. M. Marinakos, A. Chilkoti;

Duke Univ., Durham, NC.

209

Chemoselective immobilization of multiple distinct peptides on SAMs for stem cell culture

G. A. Hudalla, W. L. Murphy;

Univ. of Wisconsin-Madison, Madison, WI.

210

Development of Injectable Polymers that Cross-Link by Click Chemistry

M. Runge, M. J. Yaszemski;

Mayo Clinic, Rochester, MN.

211

Surface PEGylation via Native Chemical Ligation

E. Byun1, H. J. Lee1, S. Kang1, H. Lee2;

1#1125, Dept. of Chem. KAIST, Daejeon, KOREA, REPUBLIC OF, 2#1107, Dept. of Chem. KAIST, Daejeon, KOREA, REPUBLIC OF.

212

Modulating the Elasticity of Self-Assembled Matrices by Chemoselectively Crosslinking Distinct Fibril Populations

J. Z. Gasiorowski, J. H. Collier;

Univ. of Chicago, Chicago, IL.

Biofilm-Material Interactions (Symposia)

213

Emerging Biomaterials Strategies to Prevent Biofilm Infection

J. D. Bryers;

Univ. of Washington, Seattle, WA.

214

Targeted Cationic Peptide for the Disruption of Staphylococcus epidermidis Biofilm Formation

C. M. Hofmann, K. J. Bednar, J. M. Anderson, R. E. Marchant;

Case Western Reserve Univ., Cleveland, OH.

215

IgG biofilm adsorption is influenced by Cobalt wear debris size and can increase IL-1beta production in macrophages

A. Reddy, M. Caicedo, J. Jacobs, N. Hallab;

Rush Univ. Med. Ctr., Chicago, IL.

216

Presence of Biofilm on Passivated Metal: An Experimental Approach to Analyze the Sulzer Orthopaedics Inc. Recall

D. L. Williams1, S. Jeyapalina1, J. P. Beck1, K. L. Woodbury2, R. D. Bloebaum1;

1Univ. of Utah, Salt Lake City, UT, 2Dept. of VA, Salt Lake City, UT.

217

Effect of Protein Adsorption on Staphylococcus Epidemidis RP62A Adhesion on Polyurethane Biomaterials Surfaces

L. XU, C. A. Siedlecki;

Penn State Univ. Coll. of Med., Hershey, PA.

Emerging Frontiers in Design and Characterization of Bio-inspired Nanoscale Research & Materials

218

Functionalized Multi-Walled Carbon Nanotubes Impart Electrical Conductivity to Protein Biopolymer Matrices

C. M. Voge, J. Johns, J. P. Stegemann;

Univ. of Michigan Ann Arbor, Ann Arbor, MI.

219

Phase separation as the first step leading to hydrolytic degradation in PEG-containing polymers

S. N. Murthy, I. J. Khan, A. Luk, J. Kohn;

Rutgers Univ., Piscataway, NJ.

220

In Vitro Mechanical Testing of Collagen Nanofibrils

Z. L. Shen1, M. R. Dodge1, H. Kahn1, R. Ballarini2, S. J. Eppell1;

1Case Western Reserve Univ., Cleveland, OH, 2Univ. of Minnesota, Minneapolis, MN.

221

Charge Density Measurement of Individual Nanoparticles for the Purpose of Understanding Molecular Self-Assembly

K. E. Jarmusik1, F. R. Zypman2, S. J. Eppell1;

1Case Western Reserve Univ., Cleveland, OH, 2Yeshiva Univ., New York, NY.

222

Optimization and In Vitro Validation of Protease-Activated Quantum Dot Probes

N. J. Rohani;

Rice Univ., Houston, TX.

223

Enhanced Resistance of DNA Nanostructures to Enzymatic Digestion

J. Keum, H. Bermudez;

Univ. of Massachusetts Amherst, Amherst, MA.